Borate(1-),ammine(carboxylato)dihydro-, hydrogen, (T-4)- (9CI)
名称
[ CAS 号 ]:
74861-59-9
[ 英文名 ]:
Borate(1-),ammine(carboxylato)dihydro-, hydrogen, (T-4)- (9CI)
[英文别名 ]:
- carboxyborane ammonia complex
- ammoniumboranecarboxylate
- 2-boronoglycine
- AMMONIA-BORANECARBOXYLIC ACID
- BOROGLYCINE
- boranecarboxylicacid,ammoniumsalt
物理化学性质
[ 分子式 ]:
CH6BNO2
[ 分子量 ]:
74.87480
[ 精确质量 ]:
75.04920
[ PSA ]:
40.54000
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- ED1160000
- CHEMICAL NAME :
- Boranecarboxylic acid, ammonium salt
- CAS REGISTRY NUMBER :
- 74861-59-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C-H2-B-O2.H4-N
- MOLECULAR WEIGHT :
- 74.89
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Ascites tumor
- DOSE/DURATION :
- 100 umol/L
- REFERENCE :
- JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 74,755,1985
安全信息
[ RTECS号 ]:
ED1160000
文献
Anticancer Drugs 1 , 133, (1990)
Trimethylamine carboxyboranes including their esters and amides were shown to have antineoplastic activity in vivo against Ehrlich ascites carcinoma growth. The derivatization to the ester or amide di...
Antihyperlipidemic activity of amine cyanoboranes, amine carboxyboranes, and related compounds.J. Pharm. Sci. 70 , 339, (1981)
A series of amine cyanoboranes and amine carboxyboranes were observed to be antihyperlipidemic agents in mice; i.e., they lowered serum cholesterol and triglyceride levels significantly. These compoun...
New compounds for neutron capture therapy (NCT) and their significance.Strahlentherapie 160(12) , 764-70, (1984)
The significant advantage to be gained from combining the improved penetration of a scandium filtered beam with the reduced dose to normal tissues makes the development of 3rd generation compounds for...
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