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1-乙基-1-亚硝基脲

1-乙基-1-亚硝基脲用途

N-Nitroso-N-ethylurea is a precursor of Diazoethane with alkylating, carcinogenic, and mutagenic properties.

1-乙基-1-亚硝基脲名称

[ CAS 号 ]:
759-73-9

[ 中文名 ]:
N-亚硝基-N-乙基脲

[ 英文名 ]:
N-NITROSO-N-ETHYLUREA

[中文别名 ]:

[英文别名 ]:

Ethyl nitrosourea
Nitrosoethylurea
N-Ethyl-N-nitroso-urea
Urea,1-ethyl-1-nitroso
N-Ethylnitrosourea
MFCD00053635
Urea,N-ethyl-N-nitroso
1-ethyl-1-nitrosourea
EINECS 212-072-2
N-Nitroso-N-ethylurea

1-乙基-1-亚硝基脲物理化学性质

[ 密度 ]:
1.35g/cm3

[ 沸点 ]:
181.8ºC at 760 mmHg

[ 熔点 ]:
103-104ºC (dec)

[ 分子式 ]:
C₃H₇N₃O₂

[ 分子量 ]:
117.10700

[ 闪点 ]:
63.8ºC

[ 精确质量 ]:
117.05400

[ PSA ]:
75.76000

[ LogP ]:
0.76870

[ 折射率 ]:
1.532

[ 储存条件 ]:
−20°C

[ 稳定性 ]:
Unstable at RT, Contains approximately 40% Water, 2.0% Acetic Acid to stabilize

1-乙基-1-亚硝基脲安全信息

[ 符号 ]:

GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H312-H332-H350-H360

[ 警示性声明 ]:
P201-P280-P301 + P310-P308 + P313

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T

[ 风险声明 (欧洲) ]:
45-46-61-20/21/22

[ 安全声明 (欧洲) ]:
53-22-36/37/39-45

[ 危险品运输编码 ]:
UN 2811 6.1/PG 3

[ WGK德国 ]:
3

[ RTECS号 ]:
YT3150000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1(b)

[ 海关编码 ]:
2924199090

1-乙基-1-亚硝基脲合成路线

详细合成路线

1-乙基-1-亚硝基脲海关

[ 海关编码 ]: 2924199090

[ 中文概述 ]:
2924199090. 其他无环酰胺（包括无环氨基甲酸酯)(包括其衍生物及盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

1-乙基-1-亚硝基脲文献

Genotoxicity assessment of melamine in the in vivo Pig-a mutation assay and in a standard battery of assays.

Mutat. Res. Genet. Toxicol. Environ. Mutagen. 777 , 62-7, (2015)

The genotoxicity of melamine was evaluated with the combined Pig-a mutation/micronucleus assay, the bacterial reverse mutation assay, and the in vitro cytokinesis-block micronucleus assay (CBMN). Five...

The stress response resolution assay. I. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.

Environ. Mol. Mutagen. 54(4) , 268-80, (2013)

The events or factors that lead from normal cell function to conditions and diseases such as aging or cancer reflect complex interactions between cells and their environment. Cellular stress responses...

The stress response resolution assay. II. Quantitative assessment of environmental agent/condition effects on cellular stress resolution outcomes in epithelium.

Environ. Mol. Mutagen. 54(4) , 281-93, (2013)

Cellular stress responses consist of a complex network of pathways and linked processes that, when perturbed, are postulated to have roles in the pathogenesis of various human diseases. To assess the ...

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