硒
硒用途
1.用作分析试剂，如做催化剂。还用作芳香族化合物的脱氢剂，用于硒有机化合物的制备，电子、光学仪器的制造，高纯硒用于半导体生产中的外延扩散工序。
2.高纯硒用于制备ZnSe等化合物半导体，制备静电复印药粉等硒鼓材料及各种金属硒化物等。
3.用作制备硒整流器，光电管、光电池，复制无线电通讯、红外线偏光子、静电复印药粉、照相、冶金等的高纯材料。硒名称
[ CAS 号 ]:
7782-49-2
[ 中文名 ]:
硒
[ 英文名 ]:
Selenium
[中文别名 ]:
[英文别名 ]:
- gray selenium
- MFCD00134090
- Selenium
- elemental selenium
- EINECS 231-957-4
硒物理化学性质
[ 密度 ]:
4.81 g/mL at 25 °C(lit.)
[ 沸点 ]:
684.9 °C(lit.)
[ 熔点 ]:
217 °C(lit.)
[ 分子式 ]:
Se
[ 分子量 ]:
78.960
[ 精确质量 ]:
79.916519
[ 外观性状 ]:
暗红色-棕色至蓝黑色非晶形的固体或红色透明晶体或金属灰色至黑色晶体
[ 储存条件 ]:
库房通风低温干燥,与酸、碱、食品添加剂分开存放
[ 稳定性 ]:
Stable. Incompatible with strong acids, strong oxidizing agents and most common metals. Combustible.
[ 水溶解性 ]:
不溶
硒MSDS
硒毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- VS7700000
- CHEMICAL NAME :
- Selenium
- CAS REGISTRY NUMBER :
- 7782-49-2
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 62
- MOLECULAR FORMULA :
- Se
- MOLECULAR WEIGHT :
- 78.96
- WISWESSER LINE NOTATION :
- SE
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6700 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - other changes
- REFERENCE :
- TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 20,89,1971
- TYPE OF TEST :
- LCLo - Lowest published lethal concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 33 mg/kg/8H
- TOXIC EFFECTS :
- Blood - hemorrhage Lungs, Thorax, or Respiration - emphysema Lungs, Thorax, or Respiration - acute pulmonary edema
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,458,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine. (Chicago, IL) V.2-10, 1950-54. For publisher information, see AEHLAU. Volume(issue)/page/year: 4,458,1951
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JOBSAK Journal of Obstetrics and Gynaecology of the British Empire. (London, UK) V.1-27, 1902-15; V.28-67, 1921-60. For publisher information, see BJOGAS. Volume(issue)/page/year: 35,693,1928 ** TUMORIGENIC DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 480 mg/kg/60D-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors
- REFERENCE :
- YMBUA7 Yokohama Medical Bulletin. (Yokohama City Univ. School of Medicine, 2-33, Yokohama 232, Japan) V.1- 1950- Volume(issue)/page/year: 11,368,1960 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 134 mg/kg
- SEX/DURATION :
- multigenerations
- REFERENCE :
- AEHLAU Archives of Environmental Health. (Heldref Pub., 4000 Albemarle St., NW, Washington, DC 20016) V.1- 1960- Volume(issue)/page/year: 23,102,1971 *** REVIEWS *** ACGIH TLV-TWA 0.2 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 9,245,1975 IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 9,245,1975 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 6,459,1973 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 5,175,1972 TOXICOLOGY REVIEW CRTXB2 CRC Critical Reviews in Toxicology. (CRC Press, Inc., 2000 Corporate Blvd., NW, Boca Raton, FL 33431) V.1- 1971- Volume(issue)/page/year: 4(3),271,1976 TOXICOLOGY REVIEW JAVMA4 Journal of the American Veterinary Medical Association. (American Veterinary Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196) V.48- 1915- Volume(issue)/page/year: 164,277,1974 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 5,151,1972 TOXICOLOGY REVIEW IJMDAI Israel Journal of Medical Sciences. (POB 1435, Jerusalem 91013, Israel) V.1- 1965- Volume(issue)/page/year: 10,416,1974 TOXICOLOGY REVIEW JAMAAP JAMA, Journal of the American Medical Association. (AMA, 535 N. Dearborn St., Chicago, IL 60610) V.1- 1883- Volume(issue)/page/year: 116,562,1941 TOXICOLOGY REVIEW CHREAY Chemical Reviews. (American Chemical Soc., Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC 20037) V.1- 1924- Volume(issue)/page/year: 28,179,1941 TOXICOLOGY REVIEW ADTEAS Advances in Teratology. (New York, NY) V.1-5, 1966-72. Discontinued. Volume(issue)/page/year: 5,51,1972 TOXICOLOGY REVIEW PHREA7 Physiological Reviews. (American Physiological Soc., 9650 Rockville Pike, Bethesda, MD 20814) V.1- 1921- Volume(issue)/page/year: 23,305,1943 TOXICOLOGY REVIEW FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher information, see JFDSAZ. Volume(issue)/page/year: 7,313,1942 TOXICOLOGY REVIEW KOTTAM Kogai to Taisaku. Journal of Environmental Pollution Control. (Kogai Taisaku Gijutsu Dokokai, Shuwa-Akasaka Bldg., 9-1-244, Akasaka, Minato-ku, Tokyo 107, Japan) V.1- 1965- Volume(issue)/page/year: 11,1300,1975 TOXICOLOGY REVIEW 85CVA2 "Oncology 1970, Proceedings of the Tenth International Cancer Congress," Chicago, Year Book Medical Pub., 1971 Volume(issue)/page/year: 5,63,1970 TOXICOLOGY REVIEW PEXTAR Progress in Experimental Tumor Research. (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.1- 1960- Volume(issue)/page/year: 12,102,1969 TOXICOLOGY REVIEW BNYMAM Bulletin of the New York Academy of Medicine. (New York Academy of Medicine, 2 E. 103rd St., New York, NY 10029) Ser 2: V.1- 1925- Volume(issue)/page/year: 54,413,1978 TOXICOLOGY REVIEW AMTODM Advances in Modern Toxicology. (John Wiley & Sons, Inc., 605 Third Ave., New York, NY 10016) V.1, 1976-79. Discontinued. Volume(issue)/page/year: 3,209,1977 TOXICOLOGY REVIEW JEPTDQ Journal of Environmental Pathology and Toxicology. (Park Forest South, IL) V.1-5(3), 1977-81(?). For publisher information, see JEPOEC. Volume(issue)/page/year: 4(1),193,1980 TOXICOLOGY REVIEW MEHYDY Medical Hypotheses. (Churchill Livingstone Inc., 1560 Broadway, New York, NY 10036) V.1- 1975- Volume(issue)/page/year: 5,877,1979 TOXICOLOGY REVIEW CTOXAO Clinical Toxicology. (New York, NY) V.1-18, 1968-81. For publisher information, see JTCTDW. Volume(issue)/page/year: 17,171,1980 TOXICOLOGY REVIEW JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(1),45,1986 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.2 mg(Se)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,224,1971 OSHA PEL (Gen Indu):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.2 mg(Se)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-ARAB Republic of Egypt:TWA 0.2 mg/m3 JAN 1993 OEL-AUSTRALIA:TWA 0.2 mg(Se)/m3 JAN 1993 OEL-BELGIUM:TWA 0.2 mg/m3 JAN 1993 OEL-DENMARK:TWA 0.1 mg/m3 JAN 1993 OEL-FINLAND:TWA 0.1 mg/m3;STEL 0.3 mg/m3 JAN 1993 OEL-GERMANY:TWA 0.1 mg/m3 JAN 1993 OEL-HUNGARY:STEL 0.1 mg/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 0.2 mg/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 0.2 mg/m3 JAN 1993 OEL-POLAND:TWA 0.1 mg/m3 JAN 1993 OEL-SWEDEN:TWA 0.1 mg/m3 JAN 1993 OEL-SWITZERLAND:TWA 0.1 mg/m3 JAN 1993 OEL-TURKEY:TWA 0.2 mg/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 0.1 mg/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO SELENIUM COMPOUNDS (as Se)-air:10H TWA 0.2 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 68295 No. of Facilities: 403 (estimated) No. of Industries: 8 No. of Occupations: 10 No. of Employees: 2147 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X2074 No. of Facilities: 105 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 105 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 68295 No. of Facilities: 1102 (estimated) No. of Industries: 23 No. of Occupations: 68 No. of Employees: 27208 (estimated) No. of Female Employees: 9632 (estimated)
硒安全信息
[ 符号 ]:
GHS06, GHS08
[ 信号词 ]:
Danger
[ 危害声明 ]:
H301 + H331-H373-H413
[ 警示性声明 ]:
P261-P301 + P310-P311
[ 个人防护装备 ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ 危害码 (欧洲) ]:
T:Toxic
[ 风险声明 (欧洲) ]:
R23/25;R33;R53
[ 安全声明 (欧洲) ]:
S26-S61-S45-S28-S20/21-S28A
[ 危险品运输编码 ]:
UN 3440 6.1/PG 3
[ WGK德国 ]:
2
[ RTECS号 ]:
VS7700000
[ 包装等级 ]:
III
[ 危险类别 ]:
6.1
硒上下游产品
硒上游产品
硒下游产品
硒制备
二氧化硫还原法在搅拌下，向浓度为170g／L的二氧化硒水溶液(亚硒酸溶液，Se为130 g/L)，通入经水和稀硫酸洗涤的二氧化硫气体，在75℃充分搅拌下进行还原反应，可得到200目以上六方结晶黑色微细硒粉末。
氨气还原法 将二氧化硒的蒸气用氨气在450～500℃进行还原反应，制得硒粉末。其
将原料纯度为99．9％的硒粉，通过熔盐法提纯，可提高到99.99%。亦可用真空蒸馏法提纯 以金属硒为原料，经区域熔融后精制而成，制得高纯硒纯度为99.999%。 2.将100g的工业品硒放入385mL浓度为40%的硝酸中， 至硒不再溶解时(1～2d)，将混合物在75～80℃下加热至硒完全溶解为止。过滤后将溶液蒸发至干，并将剩余物干燥以除去未反应完的HNO3。将所制得的SeO2溶解于550mL水中。过滤并将滤液蒸发至体积为90mL后缓慢冷却，即可析出亚硒酸结晶，将结晶抽干并用少量冷水洗涤，重结晶1～2次后将其溶解在经盐酸酸化后的水中(每100g亚硒酸用水1L，水中含20～30mL相对密度为1.19盐酸)。向所得的亚硒酸溶液中通入SO2使之饱和，直至硒沉淀完全(6～8h)为止。 将沉淀转移到布氏漏斗中抽滤，并用水洗至洗出液中用AgNO3溶液检验不出Cl-离子为止，干燥后可获得灰色结晶粉末，产率为80%～85%。将所得的粉末硒加热熔融后冷却至180℃，并在此温度下维持一段时间，不久即可形成灰硒结晶。 以金属硒为原料，经区域熔融法精制，得到纯度为99.999%的高纯硒成品。
硒文献
Oncotarget 5(20) , 9710-26, (2014)
Diacylglycerol kinase (DGK)α converts diacylglycerol to phosphatidic acid. This lipid kinase sustains survival, migration and invasion of tumor cells, with no effect over untransformed cells, suggesti...
Matrix stiffening and β1 integrin drive subtype-specific fibroblast accumulation in lung cancer.Mol. Cancer Res. 13(1) , 161-73, (2015)
The crucial role of tumor-associated fibroblasts (TAF) in cancer progression is now clear in non-small cell lung cancer (NSCLC). However, therapies against TAFs are limited due to a lack of understand...
C-C chemokine receptor 2 inhibitor ameliorates hepatic steatosis by improving ER stress and inflammation in a type 2 diabetic mouse model.PLoS ONE 10(3) , e0120711, (2015)
Hepatic steatosis is the accumulation of excess fat in the liver. Recently, hepatic steatosis has become more important because it occurs in the patients with obesity, type 2 diabetes, and hyperlipide...
相关化工产品/化学物质：
相关药品：
推荐生产厂家/供应商：
公司名：上海化源世纪贸易有限公司
区域：上海市普陀区
价格：
联系人：徐经理
产品详情：硒粉
公司名：上海吉至生化科技有限公司
区域：上海市奉贤区
价格：
￥88.0/25g
￥258.0/100g
联系人：刘佳
产品详情：硒粉
公司名：上海阿拉丁生化科技股份有限公司
区域：上海市浦东新区
价格：
￥需询单/1mg
￥需询单/1g
￥需询单/1g
￥需询单/1g
联系人：阿拉丁
产品详情：硒标准溶液
查看所有供应商请点击：
相关化合物
【硒】化源网提供硒CAS号7782-49-2，硒MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询硒上化源网，专业又轻松。>>电脑版：硒
标题：硒_MSDS_用途_密度_硒CAS号【7782-49-2】_化源网 地址：https://www.chemsrc.com/amp/cas/7782-49-2_1190988.html