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2-氨基-5-氯-2'-氟二苯甲酮

2-氨基-5-氯-2'-氟二苯甲酮用途

用作药品氟奋乃静的中间体

2-氨基-5-氯-2'-氟二苯甲酮名称

[ CAS 号 ]:
784-38-3

[ 中文名 ]:
2-氨基-5-氯-2'-氟二苯甲酮

[ 英文名 ]:
2-Amino-5-chloro-2'-fluorobenzophenone

[中文别名 ]:

[英文别名 ]:

2-Amino-5-chlorophenyl 2-fluorophenyl ketone
(2-amino-5-chlorophenyl)-(2-fluorophenyl)methanone
EINECS 212-316-8
MFCD00038381
ZR DG BVR BF
2-Amino-5-chloro-2'-fluorobenzophenone
(2-Amino-5-chlorophenyl)(2-fluorophenyl)methanone

2-氨基-5-氯-2'-氟二苯甲酮物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
432.2±45.0 °C at 760 mmHg

[ 熔点 ]:
95-98 °C(lit.)

[ 分子式 ]:
C₁₃H₉ClFNO

[ 分子量 ]:
249.668

[ 闪点 ]:
215.2±28.7 °C

[ 精确质量 ]:
249.035675

[ PSA ]:
43.09000

[ LogP ]:
3.15

[ 外观性状 ]:
黄色针状晶体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.618

[ 储存条件 ]:
室温

2-氨基-5-氯-2'-氟二苯甲酮MSDS

2-氨基-5-氯-2'-氟二苯甲酮安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H315-H319-H335

[ 警示性声明 ]:
P261-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S37/39-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2922399090

2-氨基-5-氯-2'-氟二苯甲酮合成路线

2-氨基-5-氯-2'-氟二苯甲酮上下游产品

2-氨基-5-氯-2'-氟二苯甲酮上游产品

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2-氨基-5-氯-2'-氟二苯甲酮海关

[ 海关编码 ]: 2922399090

[ 中文概述 ]:
2922399090 其他氨基醛、氨基酮及其盐（包括氨基醌及其盐，但含有一种以上含氧基的除外）. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922399090 other amino-aldehydes, amino-ketones and amino-quinones, other than those containing more than one kind of oxygen function; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2-氨基-5-氯-2'-氟二苯甲酮文献

Synthesis of the impurities during the manufacture of bulk drug midazolam and separation of these impurities by HPLC.

Acta. Pharm. 63(3) , 385-96, (2013)

During the manufacture of bulk drug midazolam various impurities arised that can be the related products or degradation products. Structures of eight impurities that can arise during the manufacture o...

J. Chem. Res. Synop. , 2, (1991)

J. Am. Chem. Soc. 112 , 3969, (1990)

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