铃兰醛

铃兰醛用途

【用途一】
2-甲基-3-(4-叔丁基苯基)丙醛又称4-特丁基苯基异丁醛，是杀菌剂丁苯吗啉和苯锈啶的中间体。
【用途二】
广泛用于化妆品、香皂香精。本身有很好的花香，既可与其他花香共用，又有很好的香气适应性，与其他花香类、麝香类及木香类香气香料能很好地调合。可广泛用于百合、铃兰、紫丁香、橙花、玉兰、鸡蛋花、木香花、甜豆花型香精，也可用于素心兰、香薇东方型、木香型、麝香基和幻想型等香精。
【用途三】
该品具有甜润的百合香味，对皮肤的刺激性小，对碱稳定，广泛用于百合、丁香、玉兰、茶花以及素心兰、东方型香型日用香精。常用作肥皂、洗涤剂的香料，还可用作花香型化妆品的香料。

铃兰醛名称

[ CAS 号 ]:
80-54-6

[ 中文名 ]:
铃兰醛

[ 英文名 ]:
Lily aldehyde

[中文别名 ]:

[英文别名 ]:

UNII-T7540GJV69
3-(4-tert-butylphenyl)-2-methylpropanal
2-Methyl-3-[4-(2-methyl-2-propanyl)phenyl]propanal
Benzenepropanal, 4-(1,1-dimethylethyl)-α-methyl-
EINECS 201-289-8
Propionaldehyde, β-(4-tert-butylphenyl)-α-methyl-
MFCD00047655
VHY1&1R DX1&1&1
Lily aldehyde
Lilial

铃兰醛物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
277.7±9.0 °C at 760 mmHg

[ 分子式 ]:
C₁₄H₂₀O

[ 分子量 ]:
204.308

[ 闪点 ]:
120.9±10.2 °C

[ 精确质量 ]:
204.151413

[ PSA ]:
17.07000

[ LogP ]:
4.07

[ 外观性状 ]:
透明至略黄色液体

[ 蒸汽压 ]:
0.0±0.6 mmHg at 25°C

[ 折射率 ]:
1.491

[ 储存条件 ]:
2-8°C

铃兰醛MSDS

详细MSDS(安全技术说明书)

铃兰醛毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: MW4895000

CHEMICAL NAME :: Hydrocinnamaldehyde, p-tert-butyl-alpha-methyl-

CAS REGISTRY NUMBER :: 80-54-6

BEILSTEIN REFERENCE NO. :: 0880140

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C14-H20-O

MOLECULAR WEIGHT :: 204.34

WISWESSER LINE NOTATION :: VHY1&1R DX1&1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,659,1978 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 16,659,1978 ** REPRODUCTIVE DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

DOSE :: 500 mg/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0524035-3

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

DOSE :: 10 gm/kg

SEX/DURATION :: male 5 day(s) pre-mating

TOXIC EFFECTS :: Reproductive - Paternal Effects - testes, epididymis, sperm duct

REFERENCE :: NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0524035-3 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83218 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 19 No. of Employees: 2073 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83218 No. of Facilities: 2349 (estimated) No. of Industries: 13 No. of Occupations: 26 No. of Employees: 34278 (estimated) No. of Female Employees: 20486 (estimated)

铃兰醛安全信息

[ 符号 ]:

GHS07, GHS08, GHS09

[ 信号词 ]:
Warning

[ 危害声明 ]:
H302-H315-H317-H361-H411

[ 警示性声明 ]:
P201-P273-P280-P308 + P313-P333 + P313-P391

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R38;R51/53

[ 安全声明 (欧洲) ]:
S60

[ 危险品运输编码 ]:
UN 3082 9/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
MW4895000

[ 危险类别 ]:
9.0

[ 海关编码 ]:
2912291000

铃兰醛合成路线

详细合成路线

铃兰醛上下游产品

铃兰醛上游产品

铃兰醛下游产品

铃兰醛制备

由叔丁苯与甲醛、盐酸反应得到对叔丁基氯化苄，再与乌活托品反应生成对叔丁基苯甲醛，进一步与丙醛缩合得到前铃兰醛，最后经选择性氢化制得百合醛。

铃兰醛海关

[ 海关编码 ]: 2912291000

[ 中文概述 ]:
2912291000. 铃兰醛〔即对叔丁基-α-甲基-氧化肉桂醛〕. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最低关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 四聚甲醛报明外观

[ Summary ]:
2912291000. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

铃兰醛文献

Oestrogenic activity of benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) in MCF7 human breast cancer cells in vitro.

J. Appl. Toxicol. 29(5) , 422-34, (2009)

Benzyl salicylate, benzyl benzoate and butylphenylmethylpropional (Lilial) are added to bodycare cosmetics used around the human breast. We report here that all three compounds possess oestrogenic act...

Odorants selectively activate distinct G protein subtypes in olfactory cilia.

J. Biol. Chem. 273(27) , 16669-77, (1998)

Chemoelectrical signal transduction in olfactory neurons appears to involve intracellular reaction cascades mediated by heterotrimeric GTP-binding proteins. In this study attempts were made to identif...

Blocking adenylyl cyclase inhibits olfactory generator currents induced by "IP(3)-odors".

J. Neurophysiol. 84(1) , 575-80, (2000)

Vertebrate olfactory receptor neurons (ORNs) transduce odor stimuli into electrical signals by means of an adenylyl cyclase/cAMP second messenger cascade, but it remains widely debated whether this cA...

更多文献

铃兰醛