滴·滴混剂

滴·滴混剂名称

[ CAS 号 ]:
8003-19-8

[ 中文名 ]:
滴·滴混剂

[ 英文名 ]:
Dichloropropane-dichloropropene mixture

[英文别名 ]:

滴·滴混剂物理化学性质

[ 分子式 ]:
C6H10Cl4

[ 分子量 ]:
223.95600

[ 精确质量 ]:
221.95400

[ LogP ]:
3.83020

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

滴·滴混剂毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TX9800000
CHEMICAL NAME :
Propane, dichloro- mixed with propene, dichloro-
CAS REGISTRY NUMBER :
8003-19-8
LAST UPDATED :
199710
DATA ITEMS CITED :
16
MOLECULAR FORMULA :
C3-H6-Cl2.C3-H4-Cl2
MOLECULAR WEIGHT :
223.96

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1000 ppm/4H
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - acute pulmonary edema Liver - fatty liver degeneration
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
779 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle contraction or spasticity
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
2100 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
417 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle contraction or spasticity
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
109 mg/kg/26W-I
TOXIC EFFECTS :
Gastrointestinal - changes in structure or function of endocrine pancreas Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other hydrolases
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 ppm/7H/28D-I
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
50 ppm/6H/12W
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in bladder weight
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Mammal - pig
DOSE/DURATION :
50 ppm/7H/28D-I
TOXIC EFFECTS :
Liver - other changes Kidney, Ureter, Bladder - other changes

MUTATION DATA

TYPE OF TEST :
Mutation in microorganisms
TEST SYSTEM :
Bacteria - Salmonella typhimurium
DOSE/DURATION :
500 ug/plate
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 37,1915,1977

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