Desmetramadol

Desmetramadol is a central analgesic drug candidate. Desmetramadol inhibits 5-hydroxytryptamine type 2C receptors expressed in Xenopus Oocytes.

[ 分子式 ]:
C₁₅H₂₄ClNO₂

[ 分子量 ]:
285.81000

[ 精确质量 ]:
285.15000

[ PSA ]:
43.70000

[ LogP ]:
3.13360

详细MSDS(安全技术说明书)

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

Simultaneous Determination of Tramadol and Its Metabolite in Human Urine by the Gas Chromatography-Mass Spectrometry Method.

J. Chromatogr. Sci. 53 , 1037-43, (2015)

A sensitive and efficient method was developed for determination of tramadol and its metabolite (O-desmethyltramadol) in human urine by gas chromatography-mass spectrometry. Tramadol, O-desmethyltrama...

Pharmacokinetics of tramadol and o-desmethyltramadol in goats after intravenous and oral administration.

J. Vet. Pharmacol. Ther. 31(1) , 45-51, (2008)

The aim of this trial was to implement a method to obtain a tool for analyses of tramadol and the main metabolite, o-desmethyltramadol (M1), in goat's plasma, and to evaluate the pharmacokinetics of t...

The enantiomers of tramadol and its major metabolite inhibit peristalsis in the guinea pig small intestine via differential mechanisms.

BMC Pharmacol. 7 , 5, (2007)

Inhibition of intestinal peristalsis is a major side effect of opioid analgesics. Although tramadol is an opioid-like analgesic, its effect on gut motility is little known. Therefore, the effect of (+...

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