吉立索泮
吉立索泮名称
[ CAS 号 ]:
82230-53-3
[ 中文名 ]:
吉立索泮
[ 英文名 ]:
GYKI 51189
[英文别名 ]:
- Girisopam [INN]
- Girisopamum [INN-Latin]
- [3H]-Girisopam
- Girisopam
吉立索泮物理化学性质
[ 密度 ]:
1.23g/cm3
[ 沸点 ]:
453.9ºC at 760 mmHg
[ 分子式 ]:
C18H17ClN2O2
[ 分子量 ]:
328.79300
[ 闪点 ]:
228.3ºC
[ 精确质量 ]:
328.09800
[ PSA ]:
43.18000
[ LogP ]:
2.99780
[ 折射率 ]:
1.598
吉立索泮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DE9480200
- CHEMICAL NAME :
- 5H-2,3-Benzodiazepine, 1-(3-chlorophenyl)-7,8-dimethoxy-4-methyl-
- CAS REGISTRY NUMBER :
- 82230-53-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C18-H17-Cl-N2-O2
- MOLECULAR WEIGHT :
- 328.82
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 670 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 330 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 37,1119,1987
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