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邻硝基对氯苯胺

邻硝基对氯苯胺用途

用于生产颜料耐晒黄10G、分散黄211、紫外线吸收剂UV-326等

邻硝基对氯苯胺名称

[ CAS 号 ]:
89-63-4

[ 中文名 ]:
4-氯-2-硝基苯胺

[ 英文名 ]:
4-Chloro-2-nitroaniline

[中文别名 ]:

[英文别名 ]:

4-chloro-2-nitro-phenylamine
4-chloro-2-nitro-aniline
Red Salt Ciba VI
2-Nitro-4-chloroaniline
Benzenamine,4-chloro-2-nitro
Devol Red Salt F
Red Base Ciba VI
ZR DG BNW
EINECS 201-925-4
1-amino-2-nitro-4-chlorobenzene

邻硝基对氯苯胺物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 沸点 ]:
308.8±22.0 °C at 760 mmHg

[ 熔点 ]:
117-119 °C(lit.)

[ 分子式 ]:
C₆H₅ClN₂O₂

[ 分子量 ]:
172.569

[ 闪点 ]:
140.5±22.3 °C

[ 精确质量 ]:
172.003952

[ PSA ]:
71.84000

[ LogP ]:
2.74

[ 外观性状 ]:
黄色至橙色结晶粉末

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.646

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
INSOLUBLE

邻硝基对氯苯胺MSDS

邻硝基对氯苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX1575000

CHEMICAL NAME :: Aniline, 4-chloro-2-nitro-

CAS REGISTRY NUMBER :: 89-63-4

BEILSTEIN REFERENCE NO. :: 0512436

LAST UPDATED :: 199710

DATA ITEMS CITED :: 14

MOLECULAR FORMULA :: C6-H5-Cl-N2-O2

MOLECULAR WEIGHT :: 172.58

WISWESSER LINE NOTATION :: ZR DG BNW

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 63 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Behavioral - general anesthetic

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 20 mg/L

REFERENCE :: EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 10(Suppl 10),1,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X8936 No. of Facilities: 96 (estimated) No. of Industries: 2 No. of Occupations: 5 No. of Employees: 17827 (estimated) No. of Female Employees: 16443 (estimated)

邻硝基对氯苯胺安全信息

[ 符号 ]:

GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H300 + H310 + H330-H373-H411

[ 警示性声明 ]:
P260-P264-P273-P280-P284-P301 + P310

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
T+:Verytoxic;N:Dangerous for the environment;

[ 风险声明 (欧洲) ]:
R26/27/28;R33;R51/53

[ 安全声明 (欧洲) ]:
S28-S36/37-S45-S61-S28A

[ 危险品运输编码 ]:
UN 2237 6.1/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
BX1575000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
29214210

邻硝基对氯苯胺合成路线

邻硝基对氯苯胺上下游产品

邻硝基对氯苯胺上游产品

邻硝基对氯苯胺下游产品

邻硝基对氯苯胺制备

以2,5-二氯硝基苯与液氨为原料，先经加压氨解、结晶，然后过滤、干燥而得。原料消耗定额：2,5-二氯硝基苯（工业品）1167kg/t、液氨（工业品）230kg/t、氨水（工业品）2420kg/t。

邻硝基对氯苯胺海关

[ 海关编码 ]: 2921420090

[ 中文概述 ]:
2921420090 其他苯胺衍生物及其盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

邻硝基对氯苯胺文献

[Toxicity of 4-chloro-2-nitroaniline and 2-chloro-4-nitroaniline to isolated rat hepatocytes].

Med. Lav. 82(3) , 253-60, (1991)

The toxicity of 4-chloro-2-nitroaniline (4C2NA) and 2-chloro-4-nitroaniline (2C4NA) was investigated on isolated rat hepatocytes following 1-3 hours of exposure to 0.2 and/or 2 mM of these xenobiotics...

Disposition and metabolism of 4-chloro-2-nitroaniline in the male F344 rat.

J. Toxicol. Environ. Health A 12(2-3) , 267-82, (1983)

The disposition and metabolism of 14C-labeled 4-chloro-2-nitroaniline (CNA) was studied in male F344 rats following oral or intravenous (iv) administration. The gastrointestinal absorption of CNA was ...

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