4-methyl-5-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-1,3-thiazole,hydrochloride

名称

[ CAS 号 ]:
89663-24-1

[ 英文名 ]:
4-methyl-5-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-1,3-thiazole,hydrochloride

物理化学性质

[ 分子式 ]:
C₁₇H₂₄ClN₃S

[ 分子量 ]:
337.91100

[ 精确质量 ]:
337.13800

[ PSA ]:
47.61000

[ LogP ]:
3.92950

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TM1786700

CHEMICAL NAME :: Piperazine, 1-(2-methylphenyl)-4-(2-(4-methyl-5-thiazolyl)ethyl)- , monohydrochloride

CAS REGISTRY NUMBER :: 89663-24-1

LAST UPDATED :: 198712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H23-N3-S.Cl-H

MOLECULAR WEIGHT :: 337.95

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 450 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Behavioral - rigidity (including catalepsy)

REFERENCE :: APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 40,159,1983

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相关化合物

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