聚乙二醇油酸酯
聚乙二醇油酸酯用途
聚乙二醇油酸酯名称
[ CAS 号 ]:
9004-96-0
[ 中文名 ]:
聚乙二醇单油酸酯
[ 英文名 ]:
Polyethylene glycol monooleate
[中文别名 ]:
[英文别名 ]:
- Polyethylene glycol monooleate
聚乙二醇油酸酯物理化学性质
[ 密度 ]:
0.924 g/cm3
[ 沸点 ]:
437.5ºC at 760 mmHg
[ 分子式 ]:
C20H38O3
[ 分子量 ]:
326.51400
[ 闪点 ]:
165ºC
[ 精确质量 ]:
326.28200
[ PSA ]:
46.53000
[ LogP ]:
5.55940
[ 折射率 ]:
n20/D 1.468
[ 储存条件 ]:
室温
[ 水溶解性 ]:
toluene, ethanol and acetone: soluble (dispersible in water)
聚乙二醇油酸酯MSDS
聚乙二醇油酸酯毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MD0880000
- CHEMICAL NAME :
- Glycols, polyethylene, monooleate
- CAS REGISTRY NUMBER :
- 9004-96-0
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 7
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,299,1972
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,299,1972 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 38,428,1949 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1221 No. of Facilities: 427 (estimated) No. of Industries: 11 No. of Occupations: 18 No. of Employees: 5279 (estimated) NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - T0434 No. of Facilities: 1359 (estimated) No. of Industries: 7 No. of Occupations: 23 No. of Employees: 20925 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6804 No. of Facilities: 10990 (estimated) No. of Industries: 128 No. of Occupations: 92 No. of Employees: 210079 (estimated) No. of Female Employees: 53873 (estimated)
聚乙二醇油酸酯安全信息
[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ 危险品运输编码 ]:
NONH for all modes of transport
[ RTECS号 ]:
MD0880000
聚乙二醇油酸酯制备
将1mol油酸及催化剂量的氢氧化钾投入反应釜,逐渐升温,抽真空脱水。将水脱尽后用氮气置换釜中的空气,驱净空气后,开始通入环氧乙烷进行乙氧基化反应,反应温度维持在180~200℃,压力0.2~0.3MPa。通完环氧乙烷后,冷却降温,将料液打入中和釜用冰醋酸调pH值至6.0~7.0,再加入双氧水脱色,然后降温出料即为成品。
C17H33COOH+nCH2—CH2OKOH
C17H33COO(CH2CH2O)nH
聚乙二醇油酸酯文献
Biophys. J. 109 , 2023-36, (2015)
Cell stiffness is a sensitive indicator of physiological and pathological changes in cells, with many potential applications in biology and medicine. A new method, real-time deformability cytometry, p...
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