N,N-二乙基苯胺

N,N-二乙基苯胺用途

【用途一】
用于染料中间体、乳胶促进剂、制药、农药等
【用途二】
用作分析试剂，也用于有机合成
【用途三】
二乙基苯胺主要用于生产偶氮染料，三苯基甲烷染料，可制备碱性艳绿、碱性紫、酸性湖蓝V等；也是制药工业、彩色影片显影剂的中间体。用作分析试剂和检测锌和锰。
【用途四】
用作分析试剂和检测锌和锰。

N,N-二乙基苯胺名称

[ CAS 号 ]:
91-66-7

[ 中文名 ]:
N,N-二乙基苯胺

[ 英文名 ]:
N,N-Diethylaniline

[中文别名 ]:

[英文别名 ]:

EINECS 202-088-8
Aniline,N,N-diethyl
N,N-diethylbenzeneamine
2N2&R
N,N-Diethylaniline
N,N-Diethylanilin
MFCD00009042
N,N-Diethylbenzenamine
Benzenamine, N,N-diethyl-
Diethylphenylamine

N,N-二乙基苯胺物理化学性质

[ 密度 ]:
0.9±0.1 g/cm3

[ 沸点 ]:
213.5±9.0 °C at 760 mmHg

[ 熔点 ]:
-38 °C

[ 分子式 ]:
C₁₀H₁₅N

[ 分子量 ]:
149.233

[ 闪点 ]:
97.8±0.0 °C

[ 精确质量 ]:
149.120453

[ PSA ]:
3.24000

[ LogP ]:
3.39

[ 外观性状 ]:
淡黄色至棕色液体

[ 蒸汽密度 ]:
5.2 (vs air)

[ 蒸汽压 ]:
0.2±0.4 mmHg at 25°C

[ 折射率 ]:
1.533

[ 储存条件 ]:
库房通风低温干燥,与酸类、氧化剂、食品添加剂分开存放

[ 稳定性 ]:
Stable. Combustible. Incompatible with strong oxidizing agents, strong acids.

[ 水溶解性 ]:
14 g/L (12 ºC)

N,N-二乙基苯胺MSDS

N,N-二乙基苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX3400000

CHEMICAL NAME :: Aniline, N,N-diethyl-

CAS REGISTRY NUMBER :: 91-66-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C10-H15-N

MOLECULAR WEIGHT :: 149.26

WISWESSER LINE NOTATION :: 2N2&R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1920 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPASR* United States Environmental Protection Agency, Office of Pesticides and Toxic Substances. (U.S. Environmental Protection Agency, 401 M St., SW, Washington, DC 20460) History unknown. Volume(issue)/page/year: 8EHQ-0282-0430

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 420 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AGGHAR Archiv fuer Gewerbepathologie und Gewerbehygiene. (Berlin, Ger.) V.1-18, 1930-61. For publisher information, see IAEHDW. Volume(issue)/page/year: 15,447,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 2570 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 48(6),22,1983 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83987 No. of Facilities: 514 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 2387 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83987 No. of Facilities: 302 (estimated) No. of Industries: 3 No. of Occupations: 5 No. of Employees: 3640 (estimated) No. of Female Employees: 777 (estimated)

N,N-二乙基苯胺安全信息

[ 符号 ]:

GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331-H373-H411

[ 警示性声明 ]:
P261-P273-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R23/24/25;R33;R51/53

[ 安全声明 (欧洲) ]:
S28-S37-S45-S61-S28A

[ 危险品运输编码 ]:
UN 2432 6.1/PG 3

[ WGK德国 ]:
2

[ RTECS号 ]:
BX3400000

[ 包装等级 ]:
III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2921420090

N,N-二乙基苯胺合成路线

N,N-二乙基苯胺上下游产品

N,N-二乙基苯胺上游产品

N,N-二乙基苯胺下游产品

N,N-二乙基苯胺制备

1.氯乙烷法由苯胺与氯乙烷反应而得。因反应过程放热，当体系反应温度120℃、1.18MPa时停止加热；维持反应3h，锅内温度可达215-230℃，压力4.4-4.5MPa。泄压后水蒸气蒸馏，得粗品。根据粗品中一乙基苯胺的含量，加入苯酐酰化，再进行第二次水蒸气蒸馏，馏出物除水后即为成品。原料消耗（kg/t):苯胺645，氯乙烷（95%）1473，烧碱（42%）1230，苯酐29。 2.溴乙烷法：在装有电动搅拌器、温度计、回流冷凝器的500ml四颈反应烧瓶中，加入11ml（0.12mol）苯胺、15.75ml(0.21mol)溴乙烷、1.00g苄基三乙基氯化铵、35ml质量分数为0.35的氢氧化钠溶液，加热控制反应瓶内温度为45℃，常压下搅拌反应3h；冷却至室温，将反应液倒入分液漏斗中，静置分层。将油、水两层分离；水层用30ml乙醚分3次萃取，萃取液与油层混合。用无水硫酸镁干燥3h,过滤、蒸出乙醚。用等体积的乙酸酐处理剩佘物并保持过夜，以除去游离的仲胺。再加入质量分数为0.1的过量盐酸溶液，洗涤至酸性（PH=1-2），分出乙酰-N-乙基苯胺，用质量分数为0.25的氢氧化钠溶液碱化到PH=11-12，静置分层，分离油水两层。水层用30ml乙醚萃取2次。将萃取液与油层混合，用无水硫酸镁干燥3h，蒸去乙醚后减压蒸馏，收集沸点62-66℃/400pa的馏分，得N，N-二乙基苯胺11.18g，收率70.4%。 3.精制方法：主要杂质是N-乙基苯胺，可以通过蒸馏分离，或者将N-乙基苯胺酰基化，由于N-乙基苯胺的酰基化物挥发性低，故可将N,N-二乙基苯胺蒸馏出来。 4.亚磷酸二乙酯法：由苯胺与亚磷酸二乙酯在常压下反应而得。

N,N-二乙基苯胺海关

[ 海关编码 ]: 2921420090

[ 中文概述 ]:
2921420090 其他苯胺衍生物及其盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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