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2,5-二甲基苯胺

2,5-二甲基苯胺用途

【用途一】
用于有机合成,是农药、偶氮染料及药物的重要中间体
【用途二】
作合成偶氮染料和有机颜料的原料。

2,5-二甲基苯胺名称

[ CAS 号 ]:
95-78-3

[ 中文名 ]:
2,5-二甲基苯胺

[ 英文名 ]:
2-Amino-p-xylene

[中文别名 ]:

[英文别名 ]:

2,5-二甲基苯胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
214.9±9.0 °C at 760 mmHg

[ 熔点 ]:
11.5 °C(lit.)

[ 分子式 ]:
C8H11N

[ 分子量 ]:
121.180

[ 闪点 ]:
93.9±0.0 °C

[ 精确质量 ]:
121.089149

[ PSA ]:
26.02000

[ LogP ]:
1.86

[ 外观性状 ]:
黄色液体,当暴露在光和空气中会变暗

[ 蒸汽压 ]:
0.2±0.4 mmHg at 25°C

[ 折射率 ]:
1.559

[ 储存条件 ]:
库房通风低温干燥,与酸类、氧化剂、食品添加剂分开存放

[ 水溶解性 ]:
<0.1 g/100 mL at 18 ºC

2,5-二甲基苯胺MSDS

2,5-二甲基苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZE9100000
CHEMICAL NAME :
2,5-Xylidine
CAS REGISTRY NUMBER :
95-78-3
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C8-H11-N
MOLECULAR WEIGHT :
121.20
WISWESSER LINE NOTATION :
ZR B1 E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1297 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
841 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
13300 mg/kg/4W-I
TOXIC EFFECTS :
Liver - other changes Liver - changes in liver weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 46,305,1977 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,377,1978 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 16,377,1978 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

2,5-二甲基苯胺安全信息

[ 符号 ]:

GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331-H373-H411

[ 警示性声明 ]:
P261-P273-P280-P301 + P310-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R23/24/25;R33;R51/53

[ 安全声明 (欧洲) ]:
S28-S36/37-S45-S61-S28A

[ 危险品运输编码 ]:
UN 1711 6.1/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
ZE9100000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2921499090

2,5-二甲基苯胺合成路线

2,5-二甲基苯胺上下游产品

2,5-二甲基苯胺制备

由对二甲苯经硝化和还原制得。

2,5-二甲基苯胺海关

[ 海关编码 ]: 2921430090

[ 中文概述 ]:
2921430090 甲苯胺及其衍生物以及它们的盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 原产地证据文件及编号(例 附原产地证书, 原产于欧盟的

[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2,5-二甲基苯胺文献

Separation and analysis of dimethylaniline isomers by supercritical fluid chromatography—Electrospray ionization tandem mass spectrometry

J. Chromatogr. A. 1216(41) , 6970-3, (2009)

The assessment of human exposure to specific isomers of dimethylanilines (DMA's) is of interest for the evaluation of potential exposure-health outcome relationships. Improved analytical methods will ...

Determination method for xylidines in workplace air.

J. Occup. Health 53(3) , 230-3, (2011)

The purpose of this research was to develop a determination method for xylidines (XLDs) in workplace air for risk assessment.The characteristics of the proposed method, such as recovery, detection lim...

Oxidation of 2, 5-dimethylaniline in NH 4 F· 2.35 HF medium Characteristics of the resulting conducting polymer. Genies EM and Noel P.

J. Electroanal. Chem. Interfac. Electrochem. 296(2) , 473-490, (1990)


更多文献

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标题:2,5-二甲基苯胺_MSDS_用途_密度_CAS号【95-78-3】_化源网 地址:https://www.chemsrc.com/amp/cas/95-78-3_670777.html