2,5-二氯苯胺

2,5-二氯苯胺用途

【用途一】
用作染料和颜料中间体，也用于有机合成和制取氮肥增效剂
【用途二】
用作棉织物染色和印花的显色剂，也用作有机颜料的中间体
【用途三】
2，5-二氯苯胺是除草剂麦草畏的中间体，也是染料和氮肥增效剂的中间体。
【用途四】
该品为冰染染料大红色基GG；为印染大红色布显色剂；用于合成2,5-二氯苯胺-4-磺酸等染料中间体；也可用于制造氮肥增效剂N-2,5-二氯苯基琥珀酰胺酸。
【用途五】
染料中间体。

2,5-二氯苯胺名称

[ CAS 号 ]:
95-82-9

[ 中文名 ]:
2,5-二氯苯胺

[ 英文名 ]:
2,5-Dichloroaniline

[中文别名 ]:

[英文别名 ]:

2,5-DICHLORO-BENZENAMINE
2,5-dichloro
Azobase DCA
2,5-dichlorophenylamine
scarletbasengg
2,5-DICHLOROANILINE D
1-amino-2,5-dichlorobenzene
2,5-DI CHLORO ANILINE
fastredsggbase
Benzenamine, 2,5-dichloro-

2,5-二氯苯胺物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
251.0±0.0 °C at 760 mmHg

[ 熔点 ]:
48 °C

[ 分子式 ]:
C₆H₅Cl₂N

[ 分子量 ]:
162.017

[ 闪点 ]:
100.4±21.8 °C

[ 精确质量 ]:
160.979904

[ PSA ]:
26.02000

[ LogP ]:
2.71

[ 外观性状 ]:
淡棕色固体

[ 蒸汽压 ]:
0.0±0.5 mmHg at 25°C

[ 折射率 ]:
1.614

[ 储存条件 ]:
库房通风低温干燥,与氧化剂、食品添加剂、酸类分开存放

[ 水溶解性 ]:
ca. 0.56 g/L (20 ºC)

2,5-二氯苯胺MSDS

详细MSDS(安全技术说明书)

2,5-二氯苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BX2610000

CHEMICAL NAME :: Aniline, 2,5-dichloro-

CAS REGISTRY NUMBER :: 95-82-9

BEILSTEIN REFERENCE NO. :: 1447438

LAST UPDATED :: 199710

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C6-H5-Cl2-N

MOLECULAR WEIGHT :: 162.02

WISWESSER LINE NOTATION :: ZR BG EG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TSCAT* Office of Toxic Substances Report. (U.S. Environmental Protection Agency, Office of Toxic Substances, 401 M St., SW, Washington, DC 20460) Volume(issue)/page/year: OTS 206512

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00202

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3750 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3750 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 27300 mg/kg/13W-I

TOXIC EFFECTS :: Endocrine - changes in spleen weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - catalases

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 33(4),8,1968 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4027 No. of Facilities: 116 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 2820 (estimated) No. of Female Employees: 246 (estimated)

2,5-二氯苯胺安全信息

[ 符号 ]:

GHS06, GHS08, GHS09

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331-H373-H410

[ 警示性声明 ]:
P261-P273-P280-P301 + P310-P311-P501

[ 危害码 (欧洲) ]:
T:Toxic;N:Dangerousfortheenvironment;

[ 风险声明 (欧洲) ]:
R23/24/25;R33;R50/53

[ 安全声明 (欧洲) ]:
S28-S36/37-S45-S60-S61-S28A

[ 危险品运输编码 ]:
UN 3442 6.1/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
BX2610000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2921420090

2,5-二氯苯胺合成路线

详细合成路线

2,5-二氯苯胺上下游产品

2,5-二氯苯胺上游产品

2,5-二氯苯胺下游产品

2,5-二氯苯胺制备

1、铁粉还原法以2,5-二氯硝基苯为原料，在稀酸介质中用铁粉还原后，经中和、分离、精制而得成品。

2、加氢还原法以2,5-二氯硝基苯为原料，乙醇为介质和催化剂，在加温加压下进行加氢反应，反应产物经分离、精制而得成品。

3、其制备方法是在高压釜中加入2，5-二氯硝基苯、乙醇和铂系催化剂，在85～90℃导入氢气至3～4MPa，然后停止通氢气并保温，待压力下降稳定后即达终点，将物料倾出，脱溶结晶得产品。

2,5-二氯苯胺海关

[ 海关编码 ]: 2921420090

[ 中文概述 ]:
2921420090 其他苯胺衍生物及其盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2,5-二氯苯胺文献

Synthesis, characterization and electrical properties of poly (2, 5-, 2, 3-and 3, 5-dichloroaniline) s. Part II. Copolymers with aniline. Diaz FR, et al.

Synthetic Metals 118(1-3) , 25-31, (2001)

Tautomeric properties and crystal structure of N−[2−hydroxy−1−naphthylidene] 2,5−dichloroaniline. Yildiz M, et al.

Cryst. Res. Technol. 41(6) , 600-606, (2006)

Determination of aromatic amines by solid-phase microextraction and gas chromatography−mass spectrometry in water samples. Muller L, et al.

J. Chromatogr. A. 791(1) , 221-230, (1997)

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