alpha,alpha-diphenylpiperidine-1-propanol hydrochloride

名称

[ CAS 号 ]:
968-58-1

[ 英文名 ]:
alpha,alpha-diphenylpiperidine-1-propanol hydrochloride

[英文别名 ]:

Mitanoline
3-Piperidino-1,1-diphenyl-1-propanol hydrochloride
Pridinol hydrochloride
Pridinol-hydrochlorid
EINECS 213-529-9
Par KS-12
1,1-Diphenyl-3-piperidino-propan-1-ol,Hydrochlorid
1,1-Diphenyl-3-piperidino-1-propanol hydrochloride

物理化学性质

[ 密度 ]:
1.079g/cm3

[ 沸点 ]:
460.9ºC at 760mmHg

[ 熔点 ]:
120-121ºC

[ 分子式 ]:
C₂₀H₂₆ClNO

[ 分子量 ]:
331.88000

[ 闪点 ]:
229.9ºC

[ 精确质量 ]:
331.17000

[ PSA ]:
23.47000

[ LogP ]:
4.53840

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN2856000

CHEMICAL NAME :: 1-Piperidinepropanol, alpha,alpha-diphenyl-, hydrochloride

CAS REGISTRY NUMBER :: 968-58-1

LAST UPDATED :: 199606

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C20-H25-N-O.Cl-H

MOLECULAR WEIGHT :: 331.92

WISWESSER LINE NOTATION :: T6NTJ A2XQR&R &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 91 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 33 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 131 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 25 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 116,177,1956 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 1500 mg/kg/15W-I

TOXIC EFFECTS :: Behavioral - irritability

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 96,151,1949

安全信息

[ 海关编码 ]:
2933399090

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海关

[ 海关编码 ]: 2933399090

[ 中文概述 ]:
2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%