1,2-二亚油酰基-sn-甘油-3-磷酸胆碱

1,2-二亚油酰基-sn-甘油-3-磷酸胆碱用途

L-Dilinoleoyllecithin is a phosphatidylcholine (PC or GPCho). It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. As is the case with diacylglycerols, glycerophosphocholines can have many different combinations of fatty acids of varying lengths and saturation attached at the C-1 and C-2 positions. Fatty acids containing 16, 18 and 20 carbons are the most common. PC(18:2(9Z,12Z)/18:2(9Z,12Z)), in particular, consists of two chains of linoleic acid at the C-1 and C-2 positions. The linoleic acid moieties are derived from seed oils. Phospholipids, are ubiquitous in nature and are key components of the lipid bilayer of cells, as well as being involved in metabolism and signaling.While most phospholipids have a saturated fatty acid on C-1 and an unsaturated fatty acid on C-2 of the glycerol backbone, the fatty acid distribution at the C-1 and C-2 positions of glycerol within phospholipids is continually in flux, owing to phospholipid degradation and the continuous phospholipid remodeling that occurs while these molecules are in membranes. PCs can be synthesized via three different routes. In one route, choline is activated first by phosphorylation and then by coupling to CDP prior to attachment to phosphatidic acid. PCs can also synthesized by the addition of choline to CDP-activated 1,2-diacylglycerol. A third route to PC synthesis involves the conversion of either PS or PE to PC.

1,2-二亚油酰基-sn-甘油-3-磷酸胆碱名称

[ CAS 号 ]:
998-06-1

[ 中文名 ]:
1,2-二亚油酰基-sn-甘油-3-磷酸胆碱

[ 英文名 ]:
1,2-dilinoleoyl-sn-glycero-3-phosphocholine

[英文别名 ]:

1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE
Einecs 213-647-0
1,2-dilinoleic-glycerophosphatidylcholine
1,2-dilinolenoyl-sn-glycero-3-phosphocholine
1,2-di-O-linoleoyl-3-sn-phosphatidylcholine
DILINOLEOYL LECITHIN
L-A-PHOSPHATIDYLCHOLINE DILINOLEOYL SYNTHETIC
L-A-PHOSPHATIDYLCHOLINE DILINOLEOYL,*LYO PHILIZED

1,2-二亚油酰基-sn-甘油-3-磷酸胆碱物理化学性质

[ 分子式 ]:
C₄₄H₈₀NO₈P

[ 分子量 ]:
782.08200

[ 精确质量 ]:
781.56200

[ PSA ]:
121.00000

[ LogP ]:
12.34640

[ 外观性状 ]:
冻干的粉末

[ 储存条件 ]:
-20℃，惰性气体

1,2-二亚油酰基-sn-甘油-3-磷酸胆碱MSDS

详细MSDS(安全技术说明书)

1,2-二亚油酰基-sn-甘油-3-磷酸胆碱安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

1,2-二亚油酰基-sn-甘油-3-磷酸胆碱合成路线

详细合成路线

1,2-二亚油酰基-sn-甘油-3-磷酸胆碱文献

Unsaturated lipids protect the integral membrane peptide gramicidin A from singlet oxygen

FEBS Lett. 588(9) , 1590-5, (2014)

• Unsaturated lipids protect gramicidin channels from photosensitized inactivation. • Photosensitizer binding to membrane is independent of lipid unsaturation. • Double bonds in lipids reduce gramicid...

Phase coexistence in films composed of DLPC and DPPC: A comparison between different model membrane systems

Biochim. Biophys. Acta 1838(7) , 1823-31, (2014)

For the biophysical study of membranes, a variety of model systems have been used to measure the different parameters and to extract general principles concerning processes that may occur in cellular ...

Optimization of the Electroformation of Giant Unilamellar Vesicles (GUVs) with Unsaturated Phospholipids.

J. Membr. Biol. 248 , 827-35, (2015)

Giant unilamellar vesicles (GUV) are widely used cell membrane models. GUVs have a cell-like diameter and contain the same phospholipids that constitute cell membranes. The most frequently used protoc...

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