33095-89-5

• 常用中文名：1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE, 5-(1-METHYLETHYL)-8-PHENYL-
• 常用英文名：1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE, 5-(1-METHYLETHYL)-8-PHENYL-
• CAS号：33095-89-5
• 分子式：C₁₈H₁₆N₂O₃
• 分子量：308.33100
• 发布时间：2016-11-12 18:07:15
• 更新时间：2024-01-12 09:18:22

名称

• 英文名: 8-phenyl-5-propan-2-yl-[1,3]dioxolo[4,5-g]quinazolin-6-one
• 英文别名: 5-Isopropyl-8-phenyl-1,3-dioxolo(4,5-g)quinazolin-6(5H)-one; 1-isopropyl-4-phenyl-6,7-methylenedioxy-2(1H)-quinazolinone; 1-isopropyl-6,7-methylenedioxy-4-phenylquinazolin-2(1H)-one; 1-Isopropyl-4-phenyl-6,7-methylendioxy-2(1H)chinazolinon; 1,3-DIOXOLO(4,5-g)QUINAZOLIN-6(5H)-ONE,5-(1-METHYLETHYL)-8-PHENYL

物化性质

• 密度: 1.32g/cm3
• 沸点: 486.3ºC at 760 mmHg
• 分子式: C₁₈H₁₆N₂O₃
• 分子量: 308.33100
• 闪点: 247.9ºC
• 精确质量: 308.11600
• PSA: 53.35000
• LogP: 3.37310
• 折射率: 1.658

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : JI5050000 CHEMICAL NAME : 1,3-Dioxolo(4,5-g)quinazolin-6(5H)-one, 5-(1-methylethyl)-8-phenyl- CAS REGISTRY NUMBER : 33095-89-5 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C18-H16-N2-O3 MOLECULAR WEIGHT : 308.36 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 162 mg/kg TOXIC EFFECTS : Behavioral - general anesthetic Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 34,879,1984

合成路线

33095-91-9 ~86% 33095-89-5

文献：Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

10368-14-6 ~% 33095-89-5

文献：Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

33095-94-2 ~% 33095-89-5

文献：Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

14268-66-7 ~% 33095-89-5

文献：Houlihan, William J.; Cooke, George; Bochoven, Richard Van; Perrine, John; Takesue, Edward I.; Jukniewicz, E. Journal of Medicinal Chemistry, 1982 , vol. 25, # 9 p. 1110 - 1113

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