4728-12-5

• 常用中文名：(2,2-二甲基-1,3-二恶烷-5-基)甲醇
• 常用英文名：(2,2-Dimethyl-1,3-dioxan-5-yl)methanol
• CAS号：4728-12-5
• 分子式：C₇H₁₄O₃
• 分子量：146.184
• 发布时间：2018-12-03 15:07:07
• 更新时间：2024-01-02 18:36:42

名称

• 中文名: 5-羟基甲基-2,2-二甲基-1,3-二噁烷
• 英文名: (2,2-Dimethyl-1,3-dioxan-5-yl)methanol
• 英文别名: 5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxane; 2,2-DIMETHYL-5-HYDROXYMETHYL-1,3-DIOXANE; isopropylidene-2-hydroxymethyl-1,3-propanediol; (2,2-dimethyl-1,3-dioxane-5-yl)methanol; (2,2-Dimethyl-1,3-dioxan-5-yl)methanol; 1,3-Dioxane-5-methanol, 2,2-dimethyl-; 2,2-Dimethyl-5-(hydroxymethyl)-1,3-dixoane; (2,2-dimethyl<1,3>dioxan-5-yl)methanol

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 207.7±15.0 °C at 760 mmHg
• 熔点: 197-198°C
• 分子式: C₇H₁₄O₃
• 分子量: 146.184
• 闪点: 96.0±4.2 °C
• 精确质量: 146.094299
• PSA: 38.69000
• LogP: -0.33
• 蒸汽压: 0.1±0.9 mmHg at 25°C
• 折射率: 1.425
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi
• 海关编码: 2932999099

合成路线

82962-54-7 ~97% 4728-12-5

文献：Dubois, Joelle; Foures, Christine; Bory, Sonia; Falcou, Serge; Gaudry, Michel; Marquet, Andree Tetrahedron, 1991 , vol. 47, # 6 p. 1001 - 1012

4704-94-3 77-76-9 ~99% 4728-12-5

文献：Xu, Bin; Stephens, Andrew; Kirschenheuter, Gary; Greslin, Arthur F.; Cheng, Xiaoquin; Sennelo, Joe; Cattaneo, Marco; Zighetti, Maddalena L.; Chen, Aishe; Kim, Soon-Ai; Kim, Hak Sung; Bischofberger, Norbert; Cook, Gary; Jacobson, Kenneth A. Journal of Medicinal Chemistry, 2002 , vol. 45, # 26 p. 5694 - 5709

4704-94-3 67-64-1 ~86% 4728-12-5

文献：Eisai RandD Management Co., Ltd. Patent: EP2065379 A1, 2009 ; Location in patent: Page/Page column 18-19 ;

155818-14-7 ~80% 4728-12-5

文献：Melnick, Michael; Reich, Siegfried H.; Lewis, Kathy K.; Mitchell Jr., Lennert J.; Nguyen, Dzuy; Trippe, Anthony J.; Dawson, Heather; Davies II, Jay F.; Appelt, Krzysztof; Wu, Bor-Wen; Musick, Linda; Gehlhaar, Dan K.; Webber, Stephanie; Shetty, Bhasker; Kosa, Maha; Kahil, Deborah; Andrada, Dominic Journal of Medicinal Chemistry, 1996 , vol. 39, # 14 p. 2795 - 2811

51335-75-2 ~% 4728-12-5

文献：Chemical and Pharmaceutical Bulletin, , vol. 41, # 2 p. 339 - 345

111934-93-1 ~% 4728-12-5

文献：Tetrahedron Asymmetry, , vol. 15, # 18 p. 2811 - 2815

上下游产品

上游产品  7
82962-54-7 4704-94-3 77-76-9 67-64-1
155818-14-7 51335-75-2 111934-93-1
下游产品  2
141081-71-2 97827-17-3

海关

海关编码	2932999099
中文概述	2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%