1083326-73-1

• 常用中文名：2,4-二氟-N-(2-甲氧基-5-(4,4,5,5-四甲基-1,3,2-二氧硼杂环戊烷-2-基)吡啶-3-基)苯磺酰胺
• 常用英文名：2,4-DIFLUORO-N-(2-METHOXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDIN-3-YL)BENZENESULFONAMIDE
• CAS号：1083326-73-1
• 分子式：C₁₈H₂₁BF₂N₂O₅S
• 分子量：426.24300
• 发布时间：2018-12-18 11:52:11
• 更新时间：2024-01-10 14:23:54

名称

• 中文名: 2,4-二氟-n-[2-甲氧基-5-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-3-吡啶]-苯磺酰胺
• 英文名: 2,4-difluoro-N-[2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl]benzenesulfonamide
• 英文别名: 2,4-difluoro-N-[2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-pyridin-3-yl]-benzenesulfonamide; 2,4-difluoro-N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-yl)benzenesulfonamide; N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)-2,4-difluorobenzenesulfonamide; 2,4-difluoro-N-[2-(methyloxy)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]benzenesulfonamide; N-(2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine)-2,4-difluorophenylsulfonamide

物化性质

• 分子式: C₁₈H₂₁BF₂N₂O₅S
• 分子量: 426.24300
• 精确质量: 426.12300
• PSA: 95.13000
• LogP: 3.62220
• 储存条件: 室温

安全

• 海关编码: 2935009090

合成路线

1086063-46-8 73183-34-3 ~87% 1083326-73-1

文献：Leivers, Anna L.; Tallant, Matthew; Shotwell, J. Brad; Dickerson, Scott; Leivers, Martin R.; McDonald, Octerloney B.; Gobel, Jeff; Creech, Katrina L.; Strum, Susan L.; Mathis, Amanda; Rogers, Sabrinia; Moore, Chris B.; Botyanszki, Janos Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 2091 - 2106

893440-50-1 13918-92-8 ~60% 1083326-73-1

文献：Su, Weiguo; Zhang, Weihan; Yang, Haibin Patent: US2013/190307 A1, 2013 ; Location in patent: Paragraph 0158; 0161 ;

884495-39-0 ~% 1083326-73-1

文献：CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO); PASTOR FERNANDEZ, Joaquin; KURZ, Guido; RICO FERREIRA, Maria del Rosario; SOILAN RODRIGUEZ, David; ORTEGA SORET, Miguel Angel; MARTINEZ GONZALEZ, Sonia Patent: WO2011/121317 A1, 2011 ; WO 2011/121317 A1

152684-30-5 ~% 1083326-73-1

文献：HUTCHISON MEDIPHARMA LIMITED; SU, Weiguo; ZHANG, Weihan; YANG, Haibin Patent: WO2012/34526 A1, 2012 ; WO 2012/034526 A1

73183-34-3 ~% 1083326-73-1

文献：CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS (CNIO); PASTOR FERNANDEZ, Joaquin; KURZ, Guido; RICO FERREIRA, Maria del Rosario; SOILAN RODRIGUEZ, David; ORTEGA SORET, Miguel Angel; MARTINEZ GONZALEZ, Sonia Patent: WO2011/121317 A1, 2011 ; WO 2011/121317 A1

1083168-94-8 ~% 1083326-73-1

文献：HUTCHISON MEDIPHARMA LIMITED; SU, Weiguo; ZHANG, Weihan; YANG, Haibin Patent: WO2012/34526 A1, 2012 ; WO 2012/034526 A1

67443-38-3 ~% 1083326-73-1

文献：CALITOR SCIENCES, LLC; SUNSHINE LAKE PHARMA CO., LTD.; XI, Ning; LI, Zhuo; WANG, Tingjin; WU, Zuping; WEN, Qiuling Patent: WO2014/22128 A1, 2014 ;

13918-92-8 ~% 1083326-73-1

文献：Leivers, Anna L.; Tallant, Matthew; Shotwell, J. Brad; Dickerson, Scott; Leivers, Martin R.; McDonald, Octerloney B.; Gobel, Jeff; Creech, Katrina L.; Strum, Susan L.; Mathis, Amanda; Rogers, Sabrinia; Moore, Chris B.; Botyanszki, Janos Journal of Medicinal Chemistry, 2014 , vol. 57, # 5 p. 2091 - 2106

上下游产品

上游产品  8
1086063-46-8 73183-34-3 893440-50-1 13918-92-8
884495-39-0 152684-30-5 1083168-94-8 67443-38-3
下游产品  1
1003-03-8

海关

海关编码	2935009090
中文概述	2935009090 其他磺（酰）胺. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:35.0%
申报要素	品名, 成分含量, 用途
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%