54870-28-9

• 常用中文名：Meglitinide
• 常用英文名：Meglitinide
• CAS号：54870-28-9
• 分子式：C₁₇H₁₆ClNO₄
• 分子量：333.76600
• 发布时间：2017-10-04 21:34:37
• 更新时间：2024-01-19 17:13:21

名称

• 英文名: 4-[2-[(5-chloro-2-methoxybenzoyl)amino]ethyl]benzoic acid
• 英文别名: 4-(2-<5-chloro-2-methoxy-benzamido>-ethyl)-benzoic acid; HB 699; 4-(2-((5-Chloro-2-methoxybenzoyl)amino)ethyl)benzoic acid; Meglitinidum [INN-Latin]; 4-(2-(5-Chlor-2-methoxy-benzamido)-aethyl)benzoasaeure [German]; Meglitinido [INN-Spanish]; p-(2-(5-Chloro-o-anisamido)ethyl)benzoic acid; Meglitinide; p-<2-(5-chloro-2-methoxybenzamido)ethyl>benzoic acid

物化性质

• 密度: 1.306g/cm3
• 沸点: 536.5ºC at 760 mmHg
• 分子式: C₁₇H₁₆ClNO₄
• 分子量: 333.76600
• 闪点: 278.3ºC
• 精确质量: 333.07700
• PSA: 79.12000
• LogP: 3.59410
• 折射率: 1.6

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DG5090000 CHEMICAL NAME : Benzoic acid, 4-(2-((5-chloro-2-methoxybenzoyl)amino)ethyl)- CAS REGISTRY NUMBER : 54870-28-9 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C17-H16-Cl-N-O4 MOLECULAR WEIGHT : 333.79 WISWESSER LINE NOTATION : QVR D2MVR CG FO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 28,1081,1978

安全

• 海关编码: 2924299090

合成路线

60531-37-5 33924-49-1 ~% 54870-28-9

文献：Hoechst Aktiengesellschaft Patent: US4221815 A1, 1980 ;

1199-69-5 29568-33-0 ~36% 54870-28-9

文献：Brown, George R.; Foubister, Alan J. Journal of Medicinal Chemistry, 1984 , vol. 27, # 1 p. 79 - 81

3438-16-2 ~% 54870-28-9

文献：Kaur, Jatinder; Bhardwaj, Atul; Huang, Zhangjian; Narang, Deepak; Chen, Ting-Yueh; Plane, Frances; Knaus, Edward E. Journal of Medicinal Chemistry, 2012 , vol. 55, # 17 p. 7883 - 7891

上下游产品

上游产品  5
60531-37-5 33924-49-1 1199-69-5 29568-33-0
3438-16-2
下游产品  0

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%