886579-13-1

• 常用中文名：N-[(3-endo)-8-{(2S)-2-Hydroxy-3-[4-(methylsulfonyl)-1-piperazinyl ]propyl}-8-azabicyclo[3.2.1]oct-3-yl]-1-isopropyl-2-oxo-1,2-dihyd ro-3-quinolinecarboxamide
• 常用英文名：N-[(3-endo)-8-{(2S)-2-Hydroxy-3-[4-(methylsulfonyl)-1-piperazinyl ]propyl}-8-azabicyclo[3.2.1]oct-3-yl]-1-isopropyl-2-oxo-1,2-dihyd ro-3-quinolinecarboxamide
• CAS号：886579-13-1
• 分子式：C₂₈H₄₁N₅O₅S
• 分子量：559.72100
• 发布时间：2017-02-26 15:01:29
• 更新时间：2023-01-24 15:33:32

名称

• 英文名: N-[(3-endo)-8-{(2S)-2-Hydroxy-3-[4-(methylsulfonyl)-1-piperazinyl ]propyl}-8-azabicyclo[3.2.1]oct-3-yl]-1-isopropyl-2-oxo-1,2-dihyd ro-3-quinolinecarboxamide

物化性质

• 分子式: C₂₈H₄₁N₅O₅S
• 分子量: 559.72100
• 精确质量: 559.28300
• PSA: 127.06000
• LogP: 2.71500

合成路线

174486-91-0 886579-25-5 ~% 886579-13-1

文献：THERAVANCE, INC. Patent: US2006/100426 A1, 2006 ; Location in patent: Page/Page column 21 ; US 20060100426 A1

886579-25-5 866777-83-5 ~75% 886579-13-1

文献：McKinnell, R. Murray; Armstrong, Scott R.; Beattie, David T.; Choi, Seok-Ki; Fatheree, Paul R.; Gendron, Roland A. L.; Goldblum, Adam; Humphrey, Patrick P.; Long, Daniel D.; Marquess, Daniel G.; Shaw; Smith, Jacqueline A. M.; Turner, S. Derek; Vickery, Ross G. Journal of Medicinal Chemistry, 2009 , vol. 52, # 17 p. 5330 - 5343

上下游产品

上游产品  1
866777-83-5
下游产品  0