917885-00-8

• 常用中文名：6-fluoro-7-hydroxy-3,4-dihydro-2H-isoquinolin-1-one
• 常用英文名：6-fluoro-7-hydroxy-3,4-dihydro-2H-isoquinolin-1-one
• CAS号：917885-00-8
• 分子式：C₉H₈FNO₂
• 分子量：181.16400
• 发布时间：2017-01-04 13:26:56
• 更新时间：2024-01-05 12:30:34

名称

• 英文名: 6-fluoro-7-hydroxy-3,4-dihydro-2H-isoquinolin-1-one
• 英文别名: 1(2H)-Isoquinolinone,6-fluoro-3,4-dihydro-7-hydroxy; 6-fluoro-7-hydroxy-3.4-dihydroisoquinolin-1(2H)-one

物化性质

• 分子式: C₉H₈FNO₂
• 分子量: 181.16400
• 精确质量: 181.05400
• PSA: 52.82000
• LogP: 0.82760

合成路线

917885-01-9 ~26% 917885-00-8 1207954-11-7

文献：Shen, Zhongqi; Siva Ramamoorthy; Hatzenbuhler, Nicole T.; Evrard, Deborah A.; Childers, Wayne; Harrison, Boyd L.; Chlenov, Michael; Hornby, Geoffrey; Smith, Deborah L.; Sullivan, Kelly M.; Schechter, Lee E.; Andree, Terrance H. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 1 p. 222 - 227

82846-18-2 ~% 917885-00-8

文献：PFIZER INC.; EDWARDS, Martin Paul; KUMPF, Robert Arnold; KUNG, Pei-Pei; MCAPLINE, Indrawan James; NINKOVIC, Sacha; RUI, Eugene Yuanjin; SUTTON, Scott Channing; TATLOCK, John Howard; WYTHES, Martin James; Zehnder, Luke Raymond Patent: US2014/179667 A1, 2014 ;