892-17-1

892-17-1结构式

常用中文名：15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one
常用英文名：15,16-dihydro-11-methylcyclopenta(a)phenanthren-17-one
CAS号：892-17-1
分子式：C₁₈H₁₄O
分子量：246.30300
发布时间：2016-11-23 06:35:01
更新时间：2024-01-10 21:50:44

英文名	11-methyl-15,16-dihydrocyclopenta[a]phenanthren-17-one
英文别名	11-methyl-16,17-dihydro-15H-cyclopenta<a>-phenanthren-17-one 11-Methyl-15,16-dihydrocyclopenta<a>phenanthren-17-one 11-Methyl-15,16-dihydro-cyclopenta<a>phenanthren-17-on

密度	1.234g/cm3
沸点	470.4ºC at 760 mmHg
分子式	C₁₈H₁₄O
分子量	246.30300
闪点	211.3ºC
精确质量	246.10400
PSA	17.07000
LogP	4.43030
折射率	1.723

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GY5775000

CHEMICAL NAME :: 17H-Cyclopenta(a)phenanthren-17-one, 15,16-dihydro-11-methyl-

CAS REGISTRY NUMBER :: 892-17-1

LAST UPDATED :: 199612

DATA ITEMS CITED :: 18

MOLECULAR FORMULA :: C18-H14-O

MOLECULAR WEIGHT :: 246.32

WISWESSER LINE NOTATION :: L E5 B666 FVT&&&J N1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 150 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 360 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg/52W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2000 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 46 mg/kg/19W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 125 mg/kg/52W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 200 mg/kg/50W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 16 mg/kg/4D-C

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 120 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors

TYPE OF TEST :: Micronucleus test

TYPE OF TEST :: DNA adduct

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Rodent - hamster Lung

DOSE/DURATION :: 500 ug/L

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 43,984,1983

海关编码	2914399090

115338-39-1

~86%

892-17-1

文献：Lee, Hongmee; Harvey, Ronald G. Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4253 - 4256

24684-41-1

892-17-1

文献：Nandi, Sukumar; Panda, Kausik; Suresh; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar Tetrahedron, 2004 , vol. 60, # 16 p. 3663 - 3673

115338-38-0

892-17-1

文献：Lee, Hongmee; Harvey, Ronald G. Journal of Organic Chemistry, 1988 , vol. 53, # 18 p. 4253 - 4256

701210-10-8

892-17-1

文献：Nandi, Sukumar; Panda, Kausik; Suresh; Ila, Hiriyakkanavar; Junjappa, Hiriyakkanavar Tetrahedron, 2004 , vol. 60, # 16 p. 3663 - 3673

海关编码	2914399090
中文概述	2914399090. 其他不含其他含氧基的芳香酮. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 丙酮报明包装
Summary	2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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