CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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TU4140000
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CHEMICAL NAME :
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Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-, acetate mixed with 19-nor-17-alpha- pregna-1,3,5(10)-trien-2-yne-3,17-diol
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CAS REGISTRY NUMBER :
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8064-66-2
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LAST UPDATED :
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198910
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C24-H32-O4.C20-H24-O2
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MOLECULAR WEIGHT :
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681.00
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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10584 ug/kg/2Y-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - normocytic anemia
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REFERENCE :
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LANCAO Lancet. (7 Adam St., London WC2N 6AD, UK) V.1- 1823- Volume(issue)/page/year: 1,273,1980
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Human - woman
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DOSE/DURATION :
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41 mg/kg/2Y-I
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
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REFERENCE :
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BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 4,496,1975 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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2430 ug/kg
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SEX/DURATION :
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female 30 day(s) pre-mating
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TOXIC EFFECTS :
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Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
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REFERENCE :
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BMJOAE British Medical Journal. (British Medical Assoc., BMA House, Tavistock Sq., London WC1H 9JR, UK) V.1- 1857- Volume(issue)/page/year: 1,1318,1963
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