86436-46-6

• 常用中文名：Acetamide, 2,2,2-trifluoro-N-(5,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-
• 常用英文名：Acetamide, 2,2,2-trifluoro-N-(5,6,7,9-tetrahydro-2-hydroxy-1,3,10-trimethoxy-9-oxobenzo[a]heptalen-7-yl)-, (S)-
• CAS号：86436-46-6
• 分子式：C₂₁H₂₀F₃NO₆
• 分子量：439.38200
• 发布时间：2016-11-26 20:06:29
• 更新时间：2023-01-16 23:26:27

名称

• 英文名: 2,2,2-trifluoro-N-[(7S)-2-hydroxy-1,3,10-trimethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
• 英文别名: 2,2,2-trifluoro-n-[(7s)-2-hydroxy-1,3,10-trimethoxy-9-oxo-5,6,7,9-tetrahydrobenzo[a]heptalen-7-yl]acetamide; 2-Demethyl-N-trifluoroacetyl-deacetylcolchicine; Acetamide,N-(2-hydroxy-9-oxo-1,3,10-trimethoxy-5,6,7,9-tetrahydrobenzo(a)heptalen-7-yl)-2,2,2-trifluoro

物化性质

• 密度: 1.42g/cm3
• 沸点: 715.3ºC at 760 mmHg
• 分子式: C₂₁H₂₀F₃NO₆
• 分子量: 439.38200
• 闪点: 386.4ºC
• 精确质量: 439.12400
• PSA: 94.09000
• LogP: 3.50190
• 折射率: 1.576

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : AC3663500 CHEMICAL NAME : Acetamide, N-(2-hydroxy-9-oxo-1,3,10-trimethoxy-5,6,7,9-tetrahyd robenzo(a)heptalen-7- yl)- 2,2,2-trifluoro- CAS REGISTRY NUMBER : 86436-46-6 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C21-H20-F3-N-O6 MOLECULAR WEIGHT : 439.42 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 14 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,1365,1983