27469-61-0

• 常用中文名：1-(双(4-氯苯基)甲基)哌嗪
• 常用英文名：1-(4,4'-dichlorobenzhydryl)piperazine
• CAS号：27469-61-0
• 分子式：C₁₇H₁₈Cl₂N₂
• 分子量：321.24400
• 发布时间：2019-01-01 21:50:21
• 更新时间：2024-01-09 19:00:42

名称

• 中文名: 1-(4,4'-二氯二苯甲基)哌嗪
• 英文名: 1-[bis(4-chlorophenyl)methyl]piperazine
• 英文别名: 4,4'-Dichlorobenzhydrylpiperazine; 1-(4,4'-Dichlorobenzhydryl)piperazine; 1-<bis(4-chlorophenyl)methyl>piperazine; MFCD00191212; 4-(bis(4-chlorophenyl)methyl)piperazine

物化性质

• 密度: 1.237g/cm3
• 沸点: 425.4ºC at 760 mmHg
• 熔点: 107ºC
• 分子式: C₁₇H₁₈Cl₂N₂
• 分子量: 321.24400
• 闪点: 211.1ºC
• 精确质量: 320.08500
• PSA: 15.27000
• LogP: 4.25470
• 蒸汽压: 1.91E-07mmHg at 25°C
• 折射率: 1.599
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2933599090

合成路线

119-56-2 ~90% 27469-61-0

文献：Ortho Pharmaceutical Corporation Patent: US5021574 A1, 1991 ;

110-85-0 782-08-1 ~74% 27469-61-0

文献：Song, Kwang-Seop; Lee, Sung-Han; Chun, Hyun Ji; Kim, Jong Yup; Jung, Myung Eun; Ahn, Kwangwoo; Kim, Soo-Un; Kim, Jeongmin; Lee, Jinhwa Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 4035 - 4051

154544-61-3 ~96% 27469-61-0

文献：Younes, S.; Baziard-Mouysset, G.; Saqui-Sannes, G. de; Stigliani, J. L.; Payard, M.; et al. European Journal of Medicinal Chemistry, 1993 , vol. 28, # 12 p. 943 - 948

90-97-1 ~% 27469-61-0

文献：Weiwer, Michel; Bittker, Joshua A.; Lewis, Timothy A.; Shimada, Kenichi; Yang, Wan Seok; MacPherson, Lawrence; Dandapani, Sivaraman; Palmer, Michelle; Stockwell, Brent R.; Schreiber, Stuart L.; Munoz, Benito Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1822 - 1826

90-98-2 ~% 27469-61-0

文献：Weiwer, Michel; Bittker, Joshua A.; Lewis, Timothy A.; Shimada, Kenichi; Yang, Wan Seok; MacPherson, Lawrence; Dandapani, Sivaraman; Palmer, Michelle; Stockwell, Brent R.; Schreiber, Stuart L.; Munoz, Benito Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 4 p. 1822 - 1826

782-08-1 ~% 27469-61-0

文献：Younes, S.; Baziard-Mouysset, G.; Saqui-Sannes, G. de; Stigliani, J. L.; Payard, M.; et al. European Journal of Medicinal Chemistry, 1993 , vol. 28, # 12 p. 943 - 948

上下游产品

上游产品  6
119-56-2 110-85-0 782-08-1 154544-61-3
90-97-1 90-98-2
下游产品  0

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%