6379-69-7

• 常用中文名：Trichothec-9-en-8-one,12,13-epoxy-4-[[(2Z)-1-oxo-2-butenyl]oxy]-, (4b)-
• 常用英文名：Trichothec-9-en-8-one,12,13-epoxy-4-[[(2Z)-1-oxo-2-butenyl]oxy]-, (4b)-
• CAS号：6379-69-7
• 分子式：C₁₉H₂₄O₅
• 分子量：332.39100
• 发布时间：2016-02-10 19:12:13
• 更新时间：2024-03-12 18:43:39

名称

• 英文名: Trichothec-9-en-8-one,12,13-epoxy-4-[[(2Z)-1-oxo-2-butenyl]oxy]-, (4b)
• 英文别名: trichothecin; Trichothecine; Trichothec-9-en-8-one,12,13-epoxy-4-hydroxy-,crotonate; Wln: T4 C5 I6 C6 A B 2cg N bo ho jutj D1 eov1U2 K1 N1

物化性质

• 密度: 1.241g/cm3
• 沸点: 451.179ºC at 760 mmHg
• 分子式: C₁₉H₂₄O₅
• 分子量: 332.39100
• 闪点: 234.248ºC
• 精确质量: 332.16200
• PSA: 65.13000
• LogP: 2.34610
• 折射率: 1.562

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YD0175000 CHEMICAL NAME : Trichothecin CAS REGISTRY NUMBER : 6379-69-7 LAST UPDATED : 198910 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C19-H24-O5 MOLECULAR WEIGHT : 332.43 WISWESSER LINE NOTATION : T4 C5 I6 C6 A B 2CG N BO HO JUTJ D1 EOV1U2 K1 N1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Standard Draize test ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - guinea pig REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 4,S124,1984 ** ACUTE TOXICITY DATA ** TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Gastrointestinal - hypermotility, diarrhea REFERENCE : JGMIAN Journal of General Microbiology. (Soc. for General Microbiology, Journal Sales, 62 London Rd., Reading, RG1 5AS, UK) V.1- 1947- Volume(issue)/page/year: 12,213,1955 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DFSCDX Developments in Food Science. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.1- 1978- Volume(issue)/page/year: 4,135,1983 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 6,182,1981 *** REVIEWS *** TOXICOLOGY REVIEW NUREA8 Nutrition Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1942- Volume(issue)/page/year: 31,169,1973

安全

• 危害码 (欧洲): T+
• 风险声明 (欧洲): 26/27/28-36/37/38
• 危险品运输编码: UN 3172
• RTECS号: YD0175000
• 包装等级: I
• 危险类别: 6.1(a)

合成路线

623-68-7 ~% 6379-69-7

文献：Freeman et al. Journal of the Chemical Society, 1959 , p. 1105,1126

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