64096-87-3

• 常用中文名：四氢-2H-噻喃-4-羧酸-1,1-二氧化物
• 常用英文名：bay1251152
• CAS号：64096-87-3
• 分子式：C₆H₁₀O₄S
• 分子量：178.206
• 发布时间：2018-12-25 19:41:27
• 更新时间：2024-01-09 13:04:43

名称

• 中文名: 1,1-二氧代-六氢-1L6-硫基吡喃-4-甲酸
• 英文名: Tetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide
• 中文别名: 1,1-二氧代-六氢-1l6-硫代吡喃-4-羧酸
• 英文别名: Trifluoromethylthiazide; Flumethazide; Trifluomethylthiazide; 1,1-dioxo-hexahydro-1lambda*6*-thiopyran-4-carboxylic acid; 1,1-Dioxo-tetrahydrothiopyran-4-carboxylic acid; thian-4-carboxylic acid 1,1-dioxide; 2H-Thiopyran-4-carboxylic acid, tetrahydro-, 1,1-dioxide; Fludemil; Tetrahydro-2H-thiopyran-4-carboxylic acid 1,1-dioxide; Ademol; 1,1-Dioxo-hexahydro-1l6-thiopyran-4-carboxylic acid; Ademil; Flumetiazid; 6-Trifluormethyl-7-sulfamoyl-2H-benzo-1,2,4-thiadiazol-S,S-dioxid; 6-trifluoromethyl-7-sulfamoyl-1,2,4-benzothiadiazine-1,1-dioxide; Flumethiazid; 1,1-dioxo-tetrahydro-2H-thiopyran-4-carboxylic acid; 7-Sulfamoyl-6-trifluormethyl-1,2,4-benzothiadiazin-dioxid-(1,1); Routrax; FLUMETHIAZIDE; bay1251152

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 456.6±38.0 °C at 760 mmHg
• 熔点: 198 °C
• 分子式: C₆H₁₀O₄S
• 分子量: 178.206
• 闪点: 230.0±26.8 °C
• 精确质量: 178.029984
• PSA: 79.82000
• LogP: -1.06
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.0±2.4 mmHg at 25°C
• 折射率: 1.522
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi

合成路线

1028854-35-4 ~% 64096-87-3

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH Patent: US2010/9964 A1, 2010 ; Location in patent: Page/Page column 74 ;

917807-18-2 ~% 64096-87-3

文献：PFIZER LIMITED Patent: WO2006/136917 A1, 2006 ; Location in patent: Page/Page column 35 ; WO 2006/136917 A1

77-77-0 2033-24-1 ~% 64096-87-3

文献：TULARIK INC. Patent: WO2004/43958 A1, 2004 ; Location in patent: Page 56 ; WO 2004/043958 A1

64096-86-2 ~63% 64096-87-3

文献：Bio, Matthew M.; Hansen, Karl B.; Gipson, John Organic Process Research and Development, 2008 , vol. 12, # 5 p. 892 - 895

89489-53-2 ~% 64096-87-3

文献：Cockburn; McKay Journal of the American Chemical Society, 1954 , vol. 76, p. 5703

上下游产品

上游产品  6
1028854-35-4 917807-18-2 77-77-0 2033-24-1
64096-86-2 89489-53-2
下游产品  1
473254-28-3