848777-30-0

• 常用中文名：(S)-2-环丙基-2-(吡咯烷-2-羧酰氧基)乙酸
• 常用英文名：(S)-2-Cyclohexyl-2-(Pyrazine-2-Carboxamido)Acetic Acid
• CAS号：848777-30-0
• 分子式：C₁₃H₁₇N₃O₃
• 分子量：263.292
• 发布时间：2018-12-21 00:04:36
• 更新时间：2024-01-08 13:48:31

名称

• 中文名: (S)-2-环己基-2-(吡嗪-2-羧酰胺)乙酸
• 英文名: (2S)-2-cyclohexyl-2-(pyrazine-2-carbonylamino)acetic acid
• 英文别名: Cyclohexaneacetic acid,|A-[(2-pyrazinylcarbonyl)amino]-,(|AS); (S)-cyclohexyl-[(pyrazine-2-carbonyl)-amino]-acetic acid; (2S)-Cyclohexyl[(2-pyrazinylcarbonyl)amino]acetic acid; Cyclohexaneacetic acid, α-[(2-pyrazinylcarbonyl)amino]-, (αS)-; (S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetic acid; CYC045; cyclohexyl-[(pyrazine-2-carbonyl)-amino]-acetic acid

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 549.9±40.0 °C at 760 mmHg
• 分子式: C₁₃H₁₇N₃O₃
• 分子量: 263.292
• 闪点: 286.4±27.3 °C
• 精确质量: 263.126984
• PSA: 95.67000
• LogP: 1.26
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.566
• 储存条件: 室温

合成路线

848777-29-7 ~95% 848777-30-0

文献：VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG; RUIJTER, Eelco; ORRU, Romano; ZNABET, Anass; POLAK, Marloes; TURNER, Nicholas Patent: WO2011/103932 A1, 2011 ; Location in patent: Page/Page column 43 ;

98-97-5 1454838-80-2 ~% 848777-30-0

文献：DIPHARMA FRANCIS S.R.L.; MANTEGAZZA, Simone; ATTOLINO, Emanuele; ALLEGRINI, Pietro Patent: WO2013/131978 A1, 2013 ; Location in patent: Page/Page column 14 ;

98-97-5 ~% 848777-30-0

文献：Milo, Lawrence J.; Lai, Jack H.; Wu, Wengen; Liu, Yuxin; Maw, Hlaing; Li, Youhua; Jin, Zhiping; Shu, Ying; Poplawski, Sarah E.; Wu, Yong; Sanford, David G.; Sudmeier, James L.; Bachovchin, William W. Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4365 - 4377

145618-11-7 ~% 848777-30-0

文献：Milo, Lawrence J.; Lai, Jack H.; Wu, Wengen; Liu, Yuxin; Maw, Hlaing; Li, Youhua; Jin, Zhiping; Shu, Ying; Poplawski, Sarah E.; Wu, Yong; Sanford, David G.; Sudmeier, James L.; Bachovchin, William W. Journal of Medicinal Chemistry, 2011 , vol. 54, # 13 p. 4365 - 4377

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