111878-21-8

• 常用中文名：5-fluoro-N-trimethylsilyl-2-trimethylsilyloxypyrimidin-4-amine
• 常用英文名：5-fluoro-N-trimethylsilyl-2-trimethylsilyloxypyrimidin-4-amine
• CAS号：111878-21-8
• 分子式：C₁₀H₂₀FN₃OSi₂
• 分子量：273.45500
• 发布时间：2017-05-11 16:37:38
• 更新时间：2024-01-10 09:57:30

名称

• 英文名: 5-fluoro-N-trimethylsilyl-2-trimethylsilyloxypyrimidin-4-amine
• 英文别名: N,O-bis-(TMS) 5-fluorocytosine; (5-fluoro-2-trimethylsilanyloxy-pyrimidin-4-yl)-trimethylsilanyl-amine; 2-O-trimethylsilyl-N-(trimethylsilyl)-5-fluorocytosine; 2-trimethylsilyloxy-4-trimethylsilylamino-5-fluoropyrimidine; (5F)C(TMS)2; N,O-bis-trimethylsilane 5-fluorocytosine; 4-Pyrimidinamine,5-fluoro-N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]; bis(trimethylsilyl)-5-fluorocytosine

物化性质

• 分子式: C₁₀H₂₀FN₃OSi₂
• 分子量: 273.45500
• 精确质量: 273.11300
• PSA: 47.04000
• LogP: 3.14920

合成路线

2022-85-7 ~% 111878-21-8

文献：RANBAXY LABORATORIES LIMITED Patent: WO2007/77505 A2, 2007 ; Location in patent: Page/Page column 7; 8 ;

75-77-4 2022-85-7 ~% 111878-21-8

文献：DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC. Patent: WO2008/131062 A2, 2008 ; Location in patent: Page/Page column 35 ;

2022-85-7 999-97-3 ~% 111878-21-8

文献：Jeffrey McAtee; Schinazi, Raymond F.; Liotta, Dennis C. Journal of Organic Chemistry, 1998 , vol. 63, # 7 p. 2161 - 2167

2022-85-7 25561-30-2 ~% 111878-21-8

文献：Siddiqui; Driscoll; Marquez; Roth; Shirasaka; Mitsuya; Barchi Jr.; Kelley Journal of Medicinal Chemistry, 1992 , vol. 35, # 12 p. 2195 - 2201

2022-85-7 10416-59-8 ~% 111878-21-8

文献：Gould, Jayne H.M.; Mann, John Nucleosides and Nucleotides, 1997 , vol. 16, # 1-2 p. 193 - 213

2022-85-7 73846-26-1 ~% 111878-21-8

文献：Drew, Michael G. B.; Gorsuch, Stephen; Gould, Jayne H. M.; Mann, John Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 8 p. 969 - 978

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