905274-03-5

• 常用中文名：2-(三氟甲基)-5H-吡咯并[3,4-d]嘧啶-6(7H)-羧酸叔丁酯
• 常用英文名：5,7-Dihydro-2-(trifluoromethyl)-6H-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid 1,1-dimethylethyl ester
• CAS号：905274-03-5
• 分子式：C₁₂H₁₄F₃N₃O₂
• 分子量：289.25400
• 发布时间：2018-12-24 17:54:03
• 更新时间：2024-02-15 18:09:21

名称

• 中文名: 2-(三氟甲基)-5H-吡咯并[3,4-d]嘧啶-6(7H)-羧酸叔丁酯
• 英文名: tert-butyl 2-(trifluoromethyl)-5,7-dihydropyrrolo[3,4-d]pyrimidine-6-carboxylate
• 英文别名: 2-Trifluoromethyl-5,7-dihydro-pyrrolo[3,4-d]pyrimidine-6-carboxylic acid tert-butyl ester; tert-butyl 2-(trifluoromethyl)-5H,6H,7H-npyrrolo[3,4-d]pyrimidine-6-carboxylate; TERT-BUTYL 2-(TRIFLUOROMETHYL)-5H-PYRROLO[3,4-D]PYRIMIDINE-6(7H)-CARBOXYLATE

物化性质

• 密度: 1.334g/cm3
• 沸点: 301.8ºC at 760 mmHg
• 分子式: C₁₂H₁₄F₃N₃O₂
• 分子量: 289.25400
• 闪点: 136.4ºC
• 精确质量: 289.10400
• PSA: 55.32000
• LogP: 2.68400
• 折射率: 1.496

安全

• 海关编码: 2933990090

合成路线

157327-42-9 354-37-0 ~% 905274-03-5

文献：MERCK and CO., INC. Patent: WO2007/97931 A2, 2007 ; Location in patent: Page/Page column 32-33 ; WO 2007/097931 A2

905274-02-4 354-37-0 ~% 905274-03-5

文献：MERCK and CO., INC. Patent: WO2006/127530 A2, 2006 ; Location in patent: Page/Page column 39 ; WO 2006/127530 A2

101385-93-7 ~% 905274-03-5

文献：Biftu, Tesfaye; Qian, Xiaoxia; Chen, Ping; Feng, Dennis; Scapin, Giovanna; Gao, Ying-Duo; Cox, Jason; Sinha Roy, Ranabir; Eiermann, George; He, Huabing; Lyons, Kathy; Salituro, Gino; Patel, Sangita; Petrov, Alexander; Xu, Feng; Xu, Shiyao Sherrie; Zhang, Bei; Caldwell, Charles; Wu, Joseph K.; Weber, Ann E. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 19 p. 5361 - 5366

上下游产品

上游产品  3
157327-42-9 354-37-0 101385-93-7
下游产品  1
905274-04-6

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%