34580-69-3

• 常用中文名：3-[2-(azepan-1-yl)ethoxy]-1-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-b]pyridine,hydrochloride
• 常用英文名：3-[2-(azepan-1-yl)ethoxy]-1-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-b]pyridine,hydrochloride
• CAS号：34580-69-3
• 分子式：C₂₁H₂₄ClF₃N₄O
• 分子量：440.89000
• 发布时间：2016-01-19 21:07:38
• 更新时间：2024-02-02 23:33:53

名称

• 英文名: 3-[2-(azepan-1-yl)ethoxy]-1-[3-(trifluoromethyl)phenyl]pyrazolo[3,4-b]pyridine,hydrochloride
• 英文别名: C-Pyrazin-2-yl-methylamine; ITF 1023

物化性质

• 沸点: 467.7ºC at 760 mmHg
• 分子式: C₂₁H₂₄ClF₃N₄O
• 分子量: 440.89000
• 闪点: 236.6ºC
• 精确质量: 440.15900
• PSA: 43.18000
• LogP: 5.43400

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UR0710800 CHEMICAL NAME : 1H-Pyrazolo(3,4-b)pyridine, 3-(2-(hexahydro-1H-azepin-1-yl)ethoxy)-1-(3-(trifluor omethyl) phenyl)-, monohydrochloride CAS REGISTRY NUMBER : 34580-69-3 LAST UPDATED : 199203 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C21-H23-F3-N4-O.Cl-H MOLECULAR WEIGHT : 440.94 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Brain and Coverings - recordings from specific areas of CNS Behavioral - tremor Behavioral - muscle contraction or spasticity REFERENCE : BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 111,167,1972