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26279-89-0

26279-89-0结构式

常用中文名：Acetamide,2-chloro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
常用英文名：Acetamide,2-chloro-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
CAS号：26279-89-0
分子式：C₂₂H₂₄ClNO₆
分子量：433.88200
发布时间：2016-11-17 17:53:09
更新时间：2024-01-26 12:00:03

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英文名	2-chloro-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide
英文别名	17-Chlorocolchicine COLCHICINE,17-CHLORO Chlorcolchicine Chlorocolchicine

密度	1.31g/cm3
沸点	746.3ºC at 760mmHg
分子式	C₂₂H₂₄ClNO₆
分子量	433.88200
闪点	405.1ºC
精确质量	433.12900
PSA	83.09000
LogP	3.48140
蒸汽压	3.8E-22mmHg at 25°C
折射率	1.591

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0740000

CHEMICAL NAME :: Colchicine, 17-chloro-

CAS REGISTRY NUMBER :: 26279-89-0

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H24-Cl-N-O6

MOLECULAR WEIGHT :: 433.92

WISWESSER LINE NOTATION :: L B677 MV&T&J CO1 DO1 EO1 JMV1G NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1251 ug/kg

TOXIC EFFECTS :: Tumorigenic - active as anti-cancer agent

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,636,1981