63450-84-0

• 常用中文名：4-氨基苯甲酸甲酯盐酸盐
• 常用英文名：methyl 4-aminobenzoate,hydrochloride
• CAS号：63450-84-0
• 分子式：C₈H₁₀ClNO₂
• 分子量：187.62300
• 发布时间：2018-05-11 08:00:00
• 更新时间：2024-01-14 06:54:37

名称

• 中文名: 4-氨基苯甲酸甲酯盐酸盐
• 英文名: methyl 4-aminobenzoate,hydrochloride
• 英文别名: methyl 4-aminobenzoate hydrochloride(1:1); 4-Amino-benzoesaeure-methylester,Hydrochlorid; METHYL 4-AMINOBENZOATE HCL; Methyl 4-aminobenzoate hydrochloride; methyl-p-aminobenzoate hydrochloride; 4-amino-benzoic acid methyl ester,hydrochloride; EINECS 264-184-6

物化性质

• 密度: 1.166g/cm3
• 沸点: 299.2ºC at 760mmHg
• 熔点: 208ºC
• 分子式: C₈H₁₀ClNO₂
• 分子量: 187.62300
• 闪点: 154.9ºC
• 精确质量: 187.04000
• PSA: 52.32000
• LogP: 2.43860

MSDS

Name: Methyl 4-aminobenzoate hydrochloride 97% Material Safety Data Sheet Synonym: CAS: 63450-84-0 Section 1 - Chemical Product MSDS Name:Methyl 4-aminobenzoate hydrochloride 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 63450-84-0 Methyl 4-aminobenzoate hydrochloride 97% 264-184-6 Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Not available. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. May be harmful if swallowed. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 63450-84-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 208 - 210 deg C(decom) Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C8H10ClNO2 Molecular Weight: 188 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, reducing agents, acids, bases. Hazardous Decomposition Products: Hydrogen chloride, chlorine, nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 63450-84-0 unlisted. LD50/LC50: Not available. Carcinogenicity: Methyl 4-aminobenzoate hydrochloride - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA No information available. IMO No information available. RID/ADR No information available. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 63450-84-0: No information available. Canada CAS# 63450-84-0 is listed on Canada's NDSL List. CAS# 63450-84-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 63450-84-0 is listed on the TSCA inventory. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 安全声明 (欧洲): S24/25

合成路线

619-50-1 ~96% 63450-84-0

文献：Journal of Organic Chemistry, , vol. 74, # 18 p. 6960 - 6964

150-13-0 ~% 63450-84-0

文献：US4963539 A1, ; US 4963539 A

67-56-1 150-13-0 ~88% 63450-84-0

文献：Molecules, , vol. 13, # 5 p. 1111 - 1119

17012-22-5 ~98% 63450-84-0

文献：Research on Chemical Intermediates, , vol. 38, # 1 p. 77 - 89

82525-64-2 ~99% 63450-84-0

文献：Research on Chemical Intermediates, , vol. 38, # 1 p. 77 - 89

150-13-0 75-36-5 ~77% 63450-84-0

文献：ChemMedChem, , vol. 9, # 3 p. 638 - 648

619-45-4 ~% 63450-84-0

文献：Research on Chemical Intermediates, , vol. 38, # 1 p. 77 - 89

上下游产品

上游产品  7
619-50-1 150-13-0 67-56-1 17012-22-5
82525-64-2 75-36-5 619-45-4
下游产品  3
108583-08-0 108583-16-0 557-24-4