57314-55-3

• 常用中文名：Piperazine,1-cyclohexyl-4-(1,2-diphenylethyl)-, hydrochloride (1:2)
• 常用英文名：Piperazine,1-cyclohexyl-4-(1,2-diphenylethyl)-, hydrochloride (1:2)
• CAS号：57314-55-3
• 分子式：C₂₄H₃₃ClN₂
• 分子量：384.985
• 发布时间：2017-03-22 19:57:07
• 更新时间：2024-01-12 18:34:17

名称

• 英文名: 1-cyclohexyl-4-(1,2-diphenylethyl)piperazine,hydrochloride
• 英文别名: Piperazine, 1-cyclohexyl-4-(1,2-diphenylethyl)-, hydrochloride (1:1); 1-Cyclohexyl-4-(1,2-diphenylethyl)piperazine hydrochloride (1:1)

物化性质

• 沸点: 450.8ºC at 760 mmHg
• 分子式: C₂₄H₃₃ClN₂
• 分子量: 384.985
• 闪点: 200.6ºC
• 精确质量: 384.233215
• PSA: 6.48000
• LogP: 5.59850

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL3486500 CHEMICAL NAME : Piperazine, 1-cyclohexyl-4-(1,2-diphenylethyl)-, dihydrochloride, (+-)- CAS REGISTRY NUMBER : 57314-55-3 LAST UPDATED : 199109 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C24-H32-N2.2Cl-H MOLECULAR WEIGHT : 421.50 WISWESSER LINE NOTATION : T6N DNTJ AYR&1R& D- AL6TJ &GH 2 -+- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic Lungs, Thorax, or Respiration - dyspnea REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,105,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 136 mg/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic Lungs, Thorax, or Respiration - dyspnea REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,105,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 7800 ug/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic Lungs, Thorax, or Respiration - dyspnea REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,105,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 329 mg/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic Lungs, Thorax, or Respiration - dyspnea REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,105,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 58400 ug/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic Lungs, Thorax, or Respiration - dyspnea REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,105,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 743 mg/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic Lungs, Thorax, or Respiration - dyspnea REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,105,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 17800 ug/kg TOXIC EFFECTS : Behavioral - rigidity (including catalepsy) Behavioral - antipsychotic Lungs, Thorax, or Respiration - dyspnea REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 221,105,1976