102128-78-9

• 常用中文名：3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide
• 常用英文名：3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide
• CAS号：102128-78-9
• 分子式：C₁₃H₁₈N₂O₃
• 分子量：250.29400
• 发布时间：2016-01-05 23:46:04
• 更新时间：2024-01-13 22:10:27

名称

• 英文名: 3-(2,3-dihydro-1,4-benzodioxin-3-ylmethylamino)-N-methylpropanamide
• 英文别名: 1205 i.s.

物化性质

• 密度: 1.136g/cm3
• 沸点: 451.7ºC at 760 mmHg
• 分子式: C₁₃H₁₈N₂O₃
• 分子量: 250.29400
• 闪点: 227ºC
• 精确质量: 250.13200
• PSA: 63.08000
• LogP: 1.78330
• 蒸汽压: 2.38E-08mmHg at 25°C
• 折射率: 1.524

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UE3097200 CHEMICAL NAME : Propionamide, 3-(((1,4-benzodioxan-2-yl)methyl)amino)-N-methyl- CAS REGISTRY NUMBER : 102128-78-9 LAST UPDATED : 198910 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C13-H18-N2-O3 MOLECULAR WEIGHT : 250.33 WISWESSER LINE NOTATION : T66 BO EOT&J C1M2VM1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 75 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 90 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 105,317,1956 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular DOSE : 100 mg/kg SEX/DURATION : female 5 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : PSEBAA Proceedings of the Society for Experimental Biology and Medicine. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1903/04- Volume(issue)/page/year: 100,555,1959