142217-78-5

• 常用中文名：(2R,3S,5S)-3-苄氧基-5-[2-[[(4-甲氧基苯基)二苯基甲基]氨基]-6-苄氧基-9H-嘌呤-9-基]-2-苄氧基甲基环戊醇
• 常用英文名：5-[2-[[(4-Methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]cyclopentanol
• CAS号：142217-78-5
• 分子式：C₅₂H₄₉N₅O₅
• 分子量：823.976
• 发布时间：2018-11-22 15:47:31
• 更新时间：2024-01-08 12:58:52

名称

• 中文名: (2R,3S,5S)-3-苄氧基-5-[2-[[(4-甲氧基苯基)二苯基甲基]氨基]-6-苄氧基-9H-嘌呤-9-基]-2-苄氧基甲基环戊醇
• 英文名: (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-2-(benzyloxymethyl)cyclopentanol
• 中文别名: 恩替卡韦中间体5; 恩替卡韦中间体五; 恩替卡韦中间体N5
• 英文别名: (2R,3S,5S)-3-(Benzyloxy)-5-[6-(benzyloxy)-2-{[(4-methoxyphenyl)(diphenyl)methyl]amino}-9H-purin-9-yl]-2-[(benzyloxy)methyl]cyclopentanol; Cyclopentanol, 5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (2R,3S,5S)-; Entecavir-5; Entecavir InterMediate V; (1S,3R,4S)-3-(benzyloxy-5-[6-(benzyloxy)-2 -((4-Methoxyphenyl)diphenylMethylaMino) -9H-purin-9-yl]-2-(benzyloxyMethyl)cyclopentanol; (2R,3S,5S)-3-(Benzyloxy)-5-(6-benzyloxy)-2-(4-methyoxyphenyl)diphenylmethylamino)-9H-purin-9-yl)-2-benzyloxymethyl)cyclopentanol; (1S,2S,3S,5S)-3-(benzyloxy)-5-(6-(benzyloxy)-2-(((4-Methoxyphenyl)diphenylMethyl)aMino)-9H-purin-9-yl)-2-((benzyloxy)Methyl)cyclopentanol; (2R,3S,5S)-3-(Benzyloxy)-5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9; (1S,2S,3S,5S)-3-(Benzyloxy)-5-[6-(benzyloxy)-2-{[(4-methoxyphenyl)(diphenyl)methyl]amino}-9H-purin-9-yl]-2-[(benzyloxy)methyl]cyclopentanol; Cyclopentanol, 5-[2-[[(4-methoxyphenyl)diphenylmethyl]amino]-6-(phenylmethoxy)-9H-purin-9-yl]-3-(phenylmethoxy)-2-[(phenylmethoxy)methyl]-, (1S,2S,3S,5S)-; (1S,2S,3S,5S)-5-(2-((4-Methoxyphenyl)diphenylMethylaMino)-6-(benzyloxy)-9H-purin-9-yl)-3-(benzyloxy)-2-((benzyloxy)Methyl)cyclopentanol; Entecavir InterMediate ( # ); Entecavir Impurity 13

物化性质

• 密度: 1.2±0.1 g/cm3
• 分子式: C₅₂H₄₉N₅O₅
• 分子量: 823.976
• 精确质量: 823.373352
• PSA: 112.78000
• LogP: 9.99
• 外观性状: 固体
• 折射率: 1.646
• 储存条件: 2-8°C， 干燥

安全

• 危害码 (欧洲): Xn

合成路线

142217-77-4 14470-28-1 ~84% 142217-78-5

文献：Bisacchi; Chao; Bachard; Daris; Innaimo; Jacobs; Kocy; Lapointe; Martel; Merchant; Slusarchyk; Sundeen; Young; Colonno; Zahler Bioorganic and Medicinal Chemistry Letters, 1997 , vol. 7, # 2 p. 127 - 132

3587-60-8 ~% 142217-78-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

39939-07-6 ~% 142217-78-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

110567-22-1 ~% 142217-78-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

117641-39-1 ~% 142217-78-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

110567-21-0 ~% 142217-78-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132

4984-82-1 ~% 142217-78-5

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 2 p. 127 - 132