41666-77-7

• 常用中文名：Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-
• 常用英文名：Platinum,(1,2-ethanediamine-kN1,kN2)[propanedioato(2-)-kO1,kO3]-, (SP-4-2)-
• CAS号：41666-77-7
• 分子式：C₅H₈N₂O₄Pt
• 分子量：355.20600
• 发布时间：2016-11-17 22:33:26
• 更新时间：2024-01-30 17:04:25

名称

• 英文名: Platinum, (1,2-ethanediamine-N,N')(propanedioato(2-)-O,O')-, (SP-4-2)
• 英文别名: 1,3-Cyclopentadiene,1-ethyl-,zirconium complex

物化性质

• 沸点: 386.8ºC at 760 mmHg
• 分子式: C₅H₈N₂O₄Pt
• 分子量: 355.20600
• 闪点: 201.9ºC
• 精确质量: 355.01300
• PSA: 76.66000

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TP2505500 CHEMICAL NAME : Platinum (II), (ethylenediammine)malonato- CAS REGISTRY NUMBER : 41666-77-7 LAST UPDATED : 199509 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C5-H10-N2-O4-Pt MOLECULAR WEIGHT : 357.26 WISWESSER LINE NOTATION : Z2Z &QV1VQ &-PT- HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Human DOSE/DURATION : 1080 ug/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - paresthesis Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - other Enzymes REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 46,2148,1986 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : BICHBX Bioinorganic Chemistry. (New York, NY) V.1-9, 1971-78. Volume(issue)/page/year: 2,187,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 107 mg/kg TOXIC EFFECTS : Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes REFERENCE : CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 46,2148,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 120 mg/kg/5D-I TOXIC EFFECTS : Liver - other changes Blood - changes in bone marrow (not otherwise specified) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB80-217292

合成路线

14096-51-6 141-82-2 ~60% 41666-77-7

文献：Pasini, Alessandro; Caldirola, Cristina Inorganica Chimica Acta, 1988 , vol. 151, p. 19 - 20

23858-10-8 33878-10-3 ~% 41666-77-7

文献：Ermondi, Giuseppe; Caron, Giulia; Ravera, Mauro; Gabano, Elisabetta; Bianco, Sabrina; Platts, James A.; Osella, Domenico Dalton Transactions, 2013 , vol. 42, # 10 p. 3482 - 3489

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