CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
OH2900000
-
CHEMICAL NAME :
-
Leucine, N-(N-acetyl-3-(p-(bis(2-chloroethyl)amino)phenyl)-DL- alanyl)-, ethyl ester, L-
-
CAS REGISTRY NUMBER :
-
3577-89-7
-
LAST UPDATED :
-
199712
-
DATA ITEMS CITED :
-
3
-
MOLECULAR FORMULA :
-
C23-H35-Cl2-N3-O4
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Oral
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
680 mg/kg/10D-I
-
TOXIC EFFECTS :
-
Related to Chronic Data - death
-
REFERENCE :
-
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Intramuscular
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
215 mg/kg/10D-I
-
TOXIC EFFECTS :
-
Related to Chronic Data - death
-
REFERENCE :
-
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Rectal
-
SPECIES OBSERVED :
-
Rodent - rat
-
DOSE/DURATION :
-
590 mg/kg/10D-I
-
TOXIC EFFECTS :
-
Related to Chronic Data - death
-
REFERENCE :
-
FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 33,472,1970
|
