6961-46-2

• 常用中文名：羟乙桂胺
• 常用英文名：idrocilamide
• CAS号：6961-46-2
• 分子式：C₁₁H₁₃NO₂
• 分子量：191.22600
• 相关类别： 原料药 Anesthetic Agents 骨骼肌松弛药
• 发布时间：2018-09-22 17:49:19
• 更新时间：2024-01-19 19:26:14

名称

• 中文名: 羟乙桂胺
• 英文名: (E)-N-(2-hydroxyethyl)-3-phenylprop-2-enamide
• 英文别名: Brolitene; N-(2-Hydroxyethyl)cinnamamide; LCB 29; Idrocilamidum [INN-Latin]; Idrocilamide; Idrocilamida [INN-Spanish]; N-(Hydroxy-2 ethyl)cinnamamide; CINNAMAMIDE,N-(2-HYDROXYETHYL); Srilane; N-(Hydroxy-2-aethyl)-cinnamid; N-(2-Hydroxyethyl)cinnamide

物化性质

• 密度: 1.146 g/cm3
• 沸点: 439.4ºC at 760 mmHg
• 熔点: 100-102°
• 分子式: C₁₁H₁₃NO₂
• 分子量: 191.22600
• 精确质量: 191.09500
• PSA: 49.33000
• LogP: 1.19920

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : GD7360000 CHEMICAL NAME : Cinnamamide, N-(2-hydroxyethyl)- CAS REGISTRY NUMBER : 6961-46-2 LAST UPDATED : 199201 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C11-H13-N-O2 MOLECULAR WEIGHT : 191.25 WISWESSER LINE NOTATION : Q2MV1U1R HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >3 gm/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - irritability REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 28,28,1985 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 2950 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Behavioral - irritability REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >150 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - irritability REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,205,1974