109721-08-6

• 常用中文名：(s)-3-[[(1,1-dimethyl)dimethylsily]oxy]pentanedioic acid monomethyl ester
• 常用英文名：(s)-3-[[(1,1-dimethyl)dimethylsily]oxy]pentanedioic acid monomethyl ester
• CAS号：109721-08-6
• 分子式：C₁₂H₂₄O₅Si
• 分子量：276.40100
• 发布时间：2017-07-15 05:25:26
• 更新时间：2024-01-28 17:23:14

名称

• 英文名: (s)-3-[[(1,1-dimethyl)dimethylsily]oxy]pentanedioic acid monomethyl ester
• 英文别名: 3-t-butyldimethylsilanyloxy-1,5-pentanedioic acid monomethyl ester; hydroflumethyazide; Flutizide; Glomerulin; hydroflumenthiazide; Hidroflumetiazid; Spandiuril; Robezon; Saluron; Hydroflumethiazide; Diuredemina; Hidroalogen; Diurometon

物化性质

• 分子式: C₁₂H₂₄O₅Si
• 分子量: 276.40100
• 精确质量: 276.13900
• PSA: 72.83000
• LogP: 2.41460

安全

• 海关编码: 2931900090

合成路线

67-56-1 91424-40-7 ~96% 109721-08-6

文献：TEVA PHARMACEUTICAL INDUSTRIES LTD.; TEVA PHARMACEUTICALS USA, INC. Patent: WO2008/130638 A2, 2008 ; Location in patent: Page/Page column 31 ;

91424-40-7 ~% 109721-08-6

文献：Konoike; Araki Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7849 - 7854

109720-93-6 ~% 109721-08-6

文献：Heathcock, Clayton H.; Hadley, Cheri R.; Rosen, Terry; Theisen, Peter D.; Hecker, Scott J. Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1858 - 1873

121331-22-4 ~% 109721-08-6

文献：Karanewsky, Donald S.; Malley, Mary F.; Gougoutas, Jack Z. Journal of Organic Chemistry, 1991 , vol. 56, # 11 p. 3744 - 3747

67-56-1 113794-48-2 ~81% 109721-08-6

文献：Wang, Bo; Liu, Ji; Tang, Xiaoling; Cheng, Cheng; Gu, Jiali; Dai, Liyan; Yu, Hongwei Tetrahedron Letters, 2010 , vol. 51, # 2 p. 309 - 312

7250-55-7 ~% 109721-08-6

文献：Novak, Lajos; Rohaly, Janos; Poppe, Laszlo; Hornyanszky, Gabor; Kolonits, Pal; et al. Liebigs Annalen der Chemie, 1992 , # 2 p. 145 - 158

67-56-1 160204-81-9 ~% 109721-08-6

文献：Konoike; Araki Journal of Organic Chemistry, 1994 , vol. 59, # 25 p. 7849 - 7854

90613-44-8 18162-48-6 ~% 109721-08-6 109744-49-2

文献：Novak, Lajos; Rohaly, Janos; Poppe, Laszlo; Hornyanszky, Gabor; Kolonits, Pal; et al. Liebigs Annalen der Chemie, 1992 , # 2 p. 145 - 158

上下游产品

上游产品  7
67-56-1 91424-40-7 109720-93-6 121331-22-4
7250-55-7 90613-44-8 18162-48-6
下游产品  0

海关

海关编码	2931900090
中文概述	2931900090. 其他有机-无机化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:6.5%. 普通关税:30.0%
Summary	2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%