913376-52-0

• 常用中文名：苄基 1-(2-羟基-2-甲基丙基)-5-甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-羧酸
• 常用英文名：benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate
• CAS号：913376-52-0
• 分子式：C₂₂H₂₄N₂O₄
• 分子量：380.43700
• 发布时间：2018-12-31 18:57:20
• 更新时间：2024-01-11 20:13:24

名称

• 中文名: 苄基 1-(2-羟基-2-甲基丙基)-5-甲基-3-氧代-2-苯基-2,3-二氢-1H-吡唑-4-羧酸
• 英文名: benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenylpyrazole-4-carboxylate
• 英文别名: benzyl 1-(2-hydroxy-2-methylpropyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylate

物化性质

• 分子式: C₂₂H₂₄N₂O₄
• 分子量: 380.43700
• 精确质量: 380.17400
• PSA: 73.46000
• LogP: 3.07530

安全

• 海关编码: 2933199090

合成路线

558-30-5 ~26% 913376-52-0

文献：Amgen Inc. Patent: WO2006/116713 A1, 2006 ; Location in patent: Page/Page column 116-117 ; WO 2006/116713 A1

558-30-5 913376-49-5 ~40% 913376-52-0

文献：Siegmund, Aaron; Retz, Daniel; Xi, Ning; Dominguez, Celia; Buerli, Roland; Liu, Longbin Synlett, 2008 , # 7 p. 1005 - 1008

558-30-5 913376-54-2 ~41% 913376-52-0

文献：Liu, Longbin; Siegmund, Aaron; Xi, Ning; Kaplan-Lefko, Paula; Rex, Karen; Chen, April; Lin, Jasmine; Moriguchi, Jodi; Berry, Loren; Huang, Liyue; Teffera, Yohannes; Yang, Yajing; Zhang, Yihong; Bellon, Steven F.; Lee, Matthew; Shimanovich, Roman; Bak, Annette; Dominguez, Celia; Norman, Mark H.; Harmange, Jean-Christophe; Dussault, Isabelle; Kim, Tae-Seong Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 3688 - 3691

558-30-5 1361236-42-1 ~% 913376-52-0

文献：Liu, Longbin; Norman, Mark H.; Lee, Matthew; Xi, Ning; Siegmund, Aaron; Boezio, Alessandro A.; Booker, Shon; Choquette, Debbie; D'Angelo, Noel D.; Germain, Julie; Yang, Kevin; Yang, Yajing; Zhang, Yihong; Bellon, Steven F.; Whittington, Douglas A.; Harmange, Jean-Christophe; Dominguez, Celia; Kim, Tae-Seong; Dussault, Isabelle Journal of Medicinal Chemistry, 2012 , vol. 55, # 5 p. 1868 - 1897

上下游产品

上游产品  3
558-30-5 913376-49-5 1361236-42-1
下游产品  0

海关

海关编码	2933199090
中文概述	2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%