676-99-3

• 常用中文名：difluorophosphorylmethane
• 常用英文名：difluorophosphorylmethane
• CAS号：676-99-3
• 分子式：CH₃F₂OP
• 分子量：100.00400
• 发布时间：2017-12-15 07:40:11
• 更新时间：2024-01-09 17:59:34

名称

• 英文名: difluorophosphorylmethane
• 英文别名: methylphosphonicdifluorid; Methylphosphonyl difluoride; methylphosphonic acid difluoride; methylphosphonodifluoridate; Difluoromethylphosphine oxide; methylphosphonic difluoride; Difluoro; Methyl-phosphonsaeure-difluorid; Methyl difluorophosphite; Phosphonic difluoride,methyl; Phosphonodifluoridic acid,methyl

物化性质

• 密度: 1.384 g/cm3
• 沸点: 98-99ºC
• 熔点: -37ºC
• 分子式: CH₃F₂OP
• 分子量: 100.00400
• 精确质量: 99.98900
• PSA: 26.88000
• LogP: 1.74830
• 折射率: 1.276
• 储存条件: 库房低温,通风,干燥,与食品原料分开存放

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TA1840700 CHEMICAL NAME : Phosphonic difluoride, methyl- CAS REGISTRY NUMBER : 676-99-3 BEILSTEIN REFERENCE NO. : 1739375 LAST UPDATED : 199701 DATA ITEMS CITED : 10 MOLECULAR FORMULA : C-H3-F2-O-P MOLECULAR WEIGHT : 100.01 WISWESSER LINE NOTATION : OPFF1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1842 mg/m3/30M TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Skin and Appendages - dermatitis, other (after systemic exposure) Skin and Appendages - hair REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 15,131,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 13700 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1842 mg/m3/30M TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Behavioral - muscle weakness Behavioral - ataxia REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 15,131,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 114 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1842 mg/m3/30M TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - cyanosis Nutritional and Gross Metabolic - dehydration REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 15,131,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 25800 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 2608 mg/m3/30M TOXIC EFFECTS : Sense Organs and Special Senses (Olfaction) - effect, not otherwise specified Behavioral - aggression Lungs, Thorax, or Respiration - dyspnea REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 15,131,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 26900 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : IAEC** Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974 Volume(issue)/page/year: 17JUN1974 TYPE OF TEST : LCLo - Lowest published lethal concentration ROUTE OF EXPOSURE : Inhalation SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 1600 mg/m3 TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 4,22,1984

安全

• 风险声明 (欧洲): 34-36/37/38
• 危险品运输编码: UN 3265

合成路线

74963-92-1 ~% 676-99-3

文献：Granoth, Itshak; Segall, Yoffi; Waysbort, Daniel; Shirin, Ezra; Leader, Haim Journal of the American Chemical Society, 1980 , vol. 102, # 13 p. 4523 - 4525

115-10-6 ~% 676-99-3

文献：Kellogg Co. Patent: US2882315 , 1954 ;

79-20-9 ~% 676-99-3

文献：Kellogg Co. Patent: US2882315 , 1954 ;

99450-90-5 ~99% 10364-94-0 676-99-3

文献：Dabkowski, Wojciech; Michalski, Jan; Wasiak, Jacek; Cramer, Friedrich Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1994 , # 7 p. 817 - 820

121-45-9 ~% 381-65-7 676-99-3 353-88-8 详细

文献：Belyalov, R. U.; Kibardin, A. M.; Gazizov, T. Kh.; Pudovik, A. N. J. Gen. Chem. USSR (Engl. Transl.), 1981 , vol. 51, # 1 p. 24 - 28,19 - 23

27930-69-4 ~% 676-99-3 1426-12-6

文献：Rasumow et al. Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 194,195,196;engl.Ausg.S.194,195,196

993-13-5 ~97% 676-99-3

文献：Waerme, Rikard; Juhlin, Lars Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 12 p. 2402 - 2408

上下游产品

上游产品  5
993-13-5 115-10-6 79-20-9 121-45-9
27930-69-4
下游产品  8
107-44-8 353-88-8 756-79-6 101153-04-2
352-63-6 1511-67-7 763-14-4 673-97-2