6714-68-7

• 常用中文名：螺-(1,3-二氧戊烷-2,3'吲哚林)-2'-酮
• 常用英文名：Spiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H)-one
• CAS号：6714-68-7
• 分子式：C₁₀H₉NO₃
• 分子量：191.18300
• 发布时间：2016-07-19 14:15:19
• 更新时间：2024-01-07 11:03:13

名称

• 中文名: 螺-(1,3-二氧戊烷-2,3'吲哚林)-2'-酮
• 英文名: spiro[1,3-dioxolane-2,3'-1H-indole]-2'-one
• 英文别名: spiro<1,3-dioxolane-2,3'-indol>-2'(1'H)-one; spiro[1,3-dioxolane-2,3'-indoline]-7-one; 5'-spiro[[1,3]dioxolane-2,3'-indolin]-2'-one; spiro-(1,3-dioxolane-2,3'-indolin)-2'-one; Spiro[1,3-dioxolane-2,3'-[3H]indol]-2'(1'H)-one

物化性质

• 密度: 1.4g/cm3
• 沸点: 408.3ºC at 760 mmHg
• 熔点: 125ºC
• 分子式: C₁₀H₉NO₃
• 分子量: 191.18300
• 闪点: 200.8ºC
• 精确质量: 191.05800
• PSA: 47.56000
• LogP: 0.97630
• 折射率: 1.632
• 储存条件: 2-8℃

MSDS

Name: Spiro-(1 3-dioxolane-2 3 indolin)-2 -one 97% Material Safety Data Sheet Synonym: CAS: 6714-68-7 Section 1 - Chemical Product MSDS Name:Spiro-(1 3-dioxolane-2 3 indolin)-2 -one 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 6714-68-7 Spiro-(1,3-dioxolane-2,3'indolin)-2'-o 97% unlisted Hazard Symbols: XN Risk Phrases: 20/21/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 6714-68-7: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: tan Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 125 - 128 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H9NO3 Molecular Weight: 191 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, ammonia. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 6714-68-7 unlisted. LD50/LC50: Not available. Carcinogenicity: Spiro-(1,3-dioxolane-2,3'indolin)-2'-one - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC SOLID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2811 Packing Group: III IMO Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing Group: III RID/ADR Shipping Name: TOXIC SOLID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2811 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. WGK (Water Danger/Protection) CAS# 6714-68-7: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 6714-68-7 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 6714-68-7 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xn:Harmful;
• 风险声明 (欧洲): R20/21/22
• 安全声明 (欧洲): S36/37
• 海关编码: 2933990090

合成路线

91-56-5 107-21-1 ~99% 6714-68-7

文献：Papaioannou; Evans; Blank; Miller Organic letters, 2001 , vol. 3, # 18 p. 2879 - 2882

91-56-5 540-51-2 ~95% 6714-68-7

文献：Kumar, Kewal; Biot, Christophe; Carrere-Kremer, Severine; Kremer, Laurent; Guerardel, Yann; Roussel, Pascal; Kumar, Vipan Organometallics, 2013 , vol. 32, # 24 p. 7386 - 7398

91-56-5 107-07-3 ~78% 6714-68-7 4290-82-8 详细

文献：Heterocyclic Communications, , vol. 16, # 2-3 p. 137 - 143

74497-02-2 ~% 6714-68-7

文献：Bioorganic and Medicinal Chemistry, , vol. 21, # 9 p. 2663 - 2670

42366-35-8 ~% 6714-68-7

文献：Bioorganic and Medicinal Chemistry, , vol. 21, # 9 p. 2663 - 2670

上下游产品

上游产品  5
91-56-5 107-21-1 540-51-2 107-07-3
42366-35-8
下游产品  1
37751-39-6

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%