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2619-97-8

2619-97-8结构式
2619-97-8结构式

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英文名 Glycine,N,N-bis(2-chloroethyl)-, hydrochloride (6CI,7CI,8CI,9CI)
英文别名 N,N-Bis(2-chloraethyl)formamid
N,N-Bis-(2-chlor-aethyl)-glycin,Hydrochlorid
N,N-bis-(2-chloro-ethyl)formamide
Ameisensaeure-[bis-(2-chlor-aethyl)-amid]
2-<Bis-(2-chlorethyl)-amino>-essigsaeure
N,N-bis-(2-chloro-ethyl)-glycine,hydrochloride
FORMAMIDE,N,N-BIS(2-CHLOROETHYL)
密度 1.314g/cm3
沸点 236ºC at 760 mmHg
分子式 C6H12Cl3NO2
分子量 236.52400
闪点 96.5ºC
精确质量 234.99300
PSA 40.54000
LogP 1.65260
蒸汽压 0.0167mmHg at 25°C
折射率 1.5

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MB8480000
CHEMICAL NAME :
Glycine, N,N-bis(2-chloroethyl)-, hydrochloride
CAS REGISTRY NUMBER :
2619-97-8
LAST UPDATED :
199203
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C6-H11-Cl2-N-O2.Cl-H
MOLECULAR WEIGHT :
236.54
WISWESSER LINE NOTATION :
QV1N2G2G &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intracerebral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
113 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 18,760,1966
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
15 mg/kg
TOXIC EFFECTS :
Tumorigenic - active as anti-cancer agent
REFERENCE :
PHBUA9 Pharmaceutical Bulletin. (Tokyo, Japan) V.1-5, 1953-57. For publisher information, see CPBTAL. Volume(issue)/page/year: 2,275,1954
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Gastrointestinal - other changes Blood - leukopenia Blood - other changes
REFERENCE :
CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Primate - monkey
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Blood - leukopenia Blood - other changes
REFERENCE :
CCSUBJ Cancer Chemotherapy Reports, Part 2. (Washington, DC) V.1-5, 1964-75. For publisher information, see CTRRDO. Volume(issue)/page/year: 2,201,1965