867331-63-3

• 常用中文名：7-(2-氯-5-甲氧基苯基)-5-甲基-N-(4-(2-(吡咯烷-1-基)乙氧基)苯基)苯并[E][1,2,4]三嗪-3-胺
• 常用英文名：1,2,4-Benzotriazin-3-amine, 7-(2-chloro-5-Methoxyphenyl)-5-Methyl-N-[4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-
• CAS号：867331-63-3
• 分子式：C₂₇H₂₈ClN₅O₂
• 分子量：489.99700
• 发布时间：2018-12-31 12:51:12
• 更新时间：2024-01-18 19:06:10

名称

• 中文名: 7-(2-氯-5-甲氧基苯基)-5-甲基-N-(4-(2-(吡咯烷-1-基)乙氧基)苯基)苯并[e][1,2,4]噻嗪-3-胺
• 英文名: 7-(2-chloro-5-methoxyphenyl)-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin-3-amine
• 英文别名: 7-(2-chloro-5-methoxyphenyl)-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-1,2,4-benzotriazin-3-ylamine; [7-(2-chloro-5-methoxy-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine; 7-(2-chloro-5-methoxyphenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine

物化性质

• 分子式: C₂₇H₂₈ClN₅O₂
• 分子量: 489.99700
• 精确质量: 489.19300
• PSA: 72.40000
• LogP: 5.89130
• 外观性状: 固体
• 储存条件: 室温， 密封， 干燥

安全

• 危害码 (欧洲): Xi

合成路线

867330-72-1 1081-73-8 ~52% 867331-63-3

文献：Palanki, Moorthy S. S.; Akiyama, Hideo; Campochiaro, Peter; Cao, Jianguo; Chow, Chun P.; Dellamary, Luis; Doukas, John; Fine, Richard; Gritzen, Colleen; Hood, John D.; Hu, Steven; Kachi, Shu; Kang, Xinshan; Klebansky, Boris; Kousba, Ahmed; Lohse, Dan; Chi, Ching Mak; Martin, Michael; McPherson, Andrew; Pathak, Ved P.; Renick, Joel; Soll, Richard; Umeda, Naoyasu; Yee, Shiyin; Yokoi, Katsutoshi; Zeng, Binqi; Zhu, Hong; Noronha, Glenn Journal of Medicinal Chemistry, 2008 , vol. 51, # 6 p. 1546 - 1559

1081-73-8 ~54% 867331-63-3

文献：TargeGen, Inc. Patent: US2005/245524 A1, 2005 ; Location in patent: Page/Page column 69 ; US 20050245524 A1

677297-87-9 ~% 867331-63-3

文献：Noronha, Glenn; Barrett, Kathy; Boccia, Antonio; Brodhag, Tessa; Cao, Jianguo; Chow, Chun P.; Dneprovskaia, Elena; Doukas, John; Fine, Richard; Gong, Xianchang; Gritzen, Colleen; Gu, Hong; Hanna, Ehab; Hood, John D.; Hu, Steven; Kang, Xinshan; Key, Jann; Klebansky, Boris; Kousba, Ahmed; Li, Ge; Lohse, Dan; Mak, Chi Ching; McPherson, Andrew; Palanki, Moorthy S.S.; Pathak, Ved P.; Renick, Joel; Shi, Feng; Soll, Richard; Splittgerber, Ute; Stoughton, Silva; Tang, Suhan; Yee, Shiyin; Zeng, Binqi; Zhao, Ningning; Zhu, Hong Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 602 - 608

77811-44-0 ~% 867331-63-3

文献：Noronha, Glenn; Barrett, Kathy; Boccia, Antonio; Brodhag, Tessa; Cao, Jianguo; Chow, Chun P.; Dneprovskaia, Elena; Doukas, John; Fine, Richard; Gong, Xianchang; Gritzen, Colleen; Gu, Hong; Hanna, Ehab; Hood, John D.; Hu, Steven; Kang, Xinshan; Key, Jann; Klebansky, Boris; Kousba, Ahmed; Li, Ge; Lohse, Dan; Mak, Chi Ching; McPherson, Andrew; Palanki, Moorthy S.S.; Pathak, Ved P.; Renick, Joel; Shi, Feng; Soll, Richard; Splittgerber, Ute; Stoughton, Silva; Tang, Suhan; Yee, Shiyin; Zeng, Binqi; Zhao, Ningning; Zhu, Hong Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 602 - 608

867330-26-5 ~% 867331-63-3

文献：Noronha, Glenn; Barrett, Kathy; Boccia, Antonio; Brodhag, Tessa; Cao, Jianguo; Chow, Chun P.; Dneprovskaia, Elena; Doukas, John; Fine, Richard; Gong, Xianchang; Gritzen, Colleen; Gu, Hong; Hanna, Ehab; Hood, John D.; Hu, Steven; Kang, Xinshan; Key, Jann; Klebansky, Boris; Kousba, Ahmed; Li, Ge; Lohse, Dan; Mak, Chi Ching; McPherson, Andrew; Palanki, Moorthy S.S.; Pathak, Ved P.; Renick, Joel; Shi, Feng; Soll, Richard; Splittgerber, Ute; Stoughton, Silva; Tang, Suhan; Yee, Shiyin; Zeng, Binqi; Zhao, Ningning; Zhu, Hong Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 3 p. 602 - 608

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