251326-99-5

• 常用中文名：(1R,4S)-4-(叔丁氧基羰基氨基)环戊-2-烯羧酸甲酯
• 常用英文名：(1R-4S)-4-[[(1,1-dimethylethoxy)carbonyl]amino]- 2-Cyclopentene-1-carboxylic acid methyl ester
• CAS号：251326-99-5
• 分子式：C₁₂H₁₉NO₄
• 分子量：241.28400
• 发布时间：2018-09-03 20:16:25
• 更新时间：2024-01-10 16:22:39

名称

• 中文名: (1R-4S)-4-[[(1,1-二甲基乙氧基)羰基]氨基]- 2-环戊烯-1-羧酸甲酯
• 英文名: Methyl (1R,4S)-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)-2-cy clopentene-1-carboxylate
• 英文别名: [1R-(1|A,3|A,4|A,5|A)]-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4-dihydroxy-cyclohexanecarboxylic Acid Methyl Ester; methyl 3,5-di-O-(tert-butyldimethylsilyl)quinate; methyl (3R,5R)-3,5-bis[tert-butyl(dimethyl)silyloxy]-1,4-di-hydroxycyclohexanecarboxylate; (1R,4S)-4-tert-butoxycarbonylaminocyclopent-2-enecarboxylic acid methyl ester; (1R,4S)-N-tert-butoxycarbonyl-4-aminocyclopent-2-ene-1-carboxylic acid methyl ester; (1R,4S)-methyl 4-((t-butoxycarbonyl)amino)cyclopent-2-enecarboxylate; (1R,4S)-methyl 4-(tert-butoxycarbonylamino)cyclopent-2-enecarboxylate; Methyl (1R,3R,4S,5R)-3,5-Bis[(tert-butyl)dimethylsilyloxy]-1,4-dihydroxycyclohexane-1-carboxylate; methyl (1sn,3R,4sn,5R)-3,5-di[(tert-butyldimethylsilyl)oxy]-1,4-dihydroxy-cyclohexanecarboxylate; methyl (1R,4S)-4-[(tert-butoxycarbonyl)amino]cyclopent-2-ene-1-carboxylate; methyl quinicate; (1|A,3R,4|A,5R)-3,5-Bis[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,4-dihydroxy-cyclohexanecarboxylic Acid Methyl Ester; methyl (1R,4S)-4-((tert-butoxycarbonyl)amino)cyclopent-2-enecarboxylate; methyl (1R,4S)-4-[(tert-butyloxycarbonyl)amino]cyclopent-2-ene-1-carboxylate

物化性质

• 密度: 1.10±0.1 g/cm3(Predicted)
• 沸点: 331.2±42.0 °C(Predicted)
• 分子式: C₁₂H₁₉NO₄
• 分子量: 241.28400
• 精确质量: 241.13100
• PSA: 68.12000
• LogP: 1.83320
• 储存条件: 室温， 密封， 干燥

合成路线

24424-99-5 ~84% 251326-99-5

文献：Butora, Gabor; Goble, Stephen D.; Pastemak, Alexander; Yang, Lihu; Zhou, Changyou; Moyes, Christopher R. Patent: US2008/81803 A1, 2008 ; Location in patent: Page/Page column 37-38 ; US 20080081803 A1

151907-80-1 74-88-4 ~99% 251326-99-5

文献：Zheng, Changsheng; Cao, Ganfeng; Xia, Michael; Feng, Hao; Glenn, Joseph; Anand, Rajan; Zhang, Ke; Huang, Taisheng; Wang, Anlai; Kong, Ling; Li, Mei; Galya, Laurine; Hughes, Robert O.; Devraj, Rajesh; Morton, Phillip A.; Rogier, D. Joseph; Covington, Maryanne; Baribaud, Fred; Shin, Niu; Scherle, Peggy; Diamond, Sharon; Yeleswaram, Swamy; Vaddi, Kris; Newton, Robert; Hollis, Greg; Friedman, Steven; Metcalf, Brian; Xue, Chu-Biao Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 5 p. 1442 - 1446

49805-30-3 ~% 251326-99-5

文献：Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B. Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728

134003-04-6 ~% 251326-99-5

文献：Smith, Mark E.B.; Lloyd, Michael C.; Derrien, Nadine; Lloyd, Richard C.; Taylor, Stephen J.C.; Chaplin, David A.; Casy, Guy; McCague, Raymond Tetrahedron Asymmetry, 2001 , vol. 12, # 5 p. 703 - 705

186581-53-3 151907-80-1 ~% 251326-99-5

文献：Qiu, Jian; Pingsterhaus, Joyce M.; Silverman, Richard B. Journal of Medicinal Chemistry, 1999 , vol. 42, # 22 p. 4725 - 4728

上下游产品

上游产品  6
24424-99-5 151907-80-1 74-88-4 49805-30-3
134003-04-6 186581-53-3
下游产品  4
321744-23-4 262280-14-8 321744-21-2 321744-19-8