214287-71-5

• 常用中文名：4-(2-cyclopropylethynyl)-5,6-difluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
• 常用英文名：4-(2-cyclopropylethynyl)-5,6-difluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
• CAS号：214287-71-5
• 分子式：C₁₄H₉F₅N₂O
• 分子量：316.22600
• 发布时间：2017-01-27 18:47:40
• 更新时间：2024-01-15 00:49:51

名称

• 英文名: 4-(2-cyclopropylethynyl)-5,6-difluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
• 英文别名: Trifluromethylquinazolinone deriv. 13

物化性质

• 密度: 1.54g/cm3
• 沸点: 340.3ºC at 760 mmHg
• 分子式: C₁₄H₉F₅N₂O
• 分子量: 316.22600
• 闪点: 159.6ºC
• 精确质量: 316.06400
• PSA: 44.62000
• LogP: 3.04890
• 蒸汽压: 8.67E-05mmHg at 25°C
• 折射率: 1.554

合成路线

201218-09-9 214288-05-8 ~64% 214287-71-5

文献：Corbett, Jeffrey W.; Ko, Soo S.; Rodgers, James D.; Gearhart, Lisa A.; Magnus, Nicholas A.; Bacheler, Lee T.; Diamond, Sharon; Jeffrey, Susan; Klabe, Ronald M.; Cordova, Beverly C.; Garber, Sena; Logue, Kelly; Trainor, George L.; Anderson, Paul S.; Erickson-Viitanen, Susan K. Journal of Medicinal Chemistry, 2000 , vol. 43, # 10 p. 2019 - 2030

205756-47-4 ~% 214287-71-5

文献：Corbett, Jeffrey W.; Ko, Soo S.; Rodgers, James D.; Gearhart, Lisa A.; Magnus, Nicholas A.; Bacheler, Lee T.; Diamond, Sharon; Jeffrey, Susan; Klabe, Ronald M.; Cordova, Beverly C.; Garber, Sena; Logue, Kelly; Trainor, George L.; Anderson, Paul S.; Erickson-Viitanen, Susan K. Journal of Medicinal Chemistry, 2000 , vol. 43, # 10 p. 2019 - 2030

214288-04-7 ~% 214287-71-5

文献：Corbett, Jeffrey W.; Ko, Soo S.; Rodgers, James D.; Gearhart, Lisa A.; Magnus, Nicholas A.; Bacheler, Lee T.; Diamond, Sharon; Jeffrey, Susan; Klabe, Ronald M.; Cordova, Beverly C.; Garber, Sena; Logue, Kelly; Trainor, George L.; Anderson, Paul S.; Erickson-Viitanen, Susan K. Journal of Medicinal Chemistry, 2000 , vol. 43, # 10 p. 2019 - 2030

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201218-09-9 205756-47-4
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