633-59-0

• 常用中文名：1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, hydrochloride (1:2)
• 常用英文名：1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, hydrochloride (1:2)
• CAS号：633-59-0
• 分子式：C₂₂H₂₆Cl₂N₂OS
• 分子量：437.42600
• 发布时间：2016-07-10 07:38:10
• 更新时间：2024-01-07 19:37:21

名称

• 英文名: 1-Piperazineethanol,4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, hydrochloride (1:2)
• 英文别名: CLOPENTHIXOL DIHYDROCHLORIDE; 2-(4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazin-1-yl)ethanol dihydrochloride; 2-[4-[3-(2-Chlorothioxanthen-9-Ylidene)Propyl]Piperazin-1-Yl]Ethanol Dihydrochloride; 4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]piperazine-1-ethanol dihydrochloride

物化性质

• 分子式: C₂₂H₂₆Cl₂N₂OS
• 分子量: 437.42600
• 精确质量: 436.11400
• PSA: 52.01000
• LogP: 4.91410

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL8575000 CHEMICAL NAME : 1-Piperazineethanol, 4-(3-(2-chlorothioxanthen-9-ylidene)propyl)-, dihydrochloride CAS REGISTRY NUMBER : 633-59-0 LAST UPDATED : 199507 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C22-H25-Cl-N2-O-S.2Cl-H MOLECULAR WEIGHT : 473.92 WISWESSER LINE NOTATION : T C666 BS IYJ EG IU3- AT6N DNTJ D2Q HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 660 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 105 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 125 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 560 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 222 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,67,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 111 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #3996211