51003-83-9

• 常用中文名：2-n-BUTYL-3-DIMETHYLAMINO-5,6-METHYL-ENE DIOXYINDENE HYDROCHLORIDE
• 常用英文名：2-n-BUTYL-3-DIMETHYLAMINO-5,6-METHYL-ENE DIOXYINDENE HYDROCHLORIDE
• CAS号：51003-83-9
• 分子式：C₁₆H₂₂ClNO₂
• 分子量：295.80400
• 发布时间：2016-03-04 12:32:40
• 更新时间：2024-10-10 12:33:16

名称

• 英文名: 6-butyl-N,N-dimethyl-7H-cyclopenta[f][1,3]benzodioxol-7-amine,hydrochloride
• 英文别名: 2-Butyl-5,6-methylenedioxyindene-1-dimethylammonium hydrochloride; 2-n-Butyl-3-dimethylamino-5,6-methylenedioxyindenehydrochloride; bu-MDI; bu-MDI HCl

物化性质

• 密度: 1.13g/cm3
• 沸点: 367.6ºC at 760 mmHg
• 分子式: C₁₆H₂₂ClNO₂
• 分子量: 295.80400
• 闪点: 126.5ºC
• 精确质量: 295.13400
• PSA: 21.70000
• LogP: 4.40720
• 折射率: 1.581

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NK8926000 CHEMICAL NAME : 5H-Indeno(5,6-d)-1,3-dioxole, 6-butyl-5-dimethylamino-, hydrochloride CAS REGISTRY NUMBER : 51003-83-9 LAST UPDATED : 199606 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C16-H21-N-O2.Cl-H MOLECULAR WEIGHT : 295.84 WISWESSER LINE NOTATION : T C565 DO FO EH JHJ JN1&1 K4 &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 240 mg/kg TOXIC EFFECTS : Gastrointestinal - decreased motility or constipation REFERENCE : RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 185 mg/kg TOXIC EFFECTS : Gastrointestinal - decreased motility or constipation REFERENCE : RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 32 mg/kg TOXIC EFFECTS : Behavioral - altered sleep time (including change in righting reflex) Behavioral - changes in motor activity (specific assay) Gastrointestinal - decreased motility or constipation REFERENCE : RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979 ** OTHER MULTIPLE DOSE TOXICITY DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 735 mg/kg/4W-I TOXIC EFFECTS : Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - dehydrogenases REFERENCE : RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 647 mg/kg/2W-I TOXIC EFFECTS : Related to Chronic Data - death REFERENCE : RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 26,85,1979